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Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease characterized by patchy scarring of the distal lung with limited therapeutic options and poor prognosis. Here, we show that conditional deletion of the ubiquitin ligase Nedd4-2 (Nedd4l) in lung epithelial cells in...

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Detalles Bibliográficos
Autores principales:	Duerr, Julia, Leitz, Dominik H. W., Szczygiel, Magdalena, Dvornikov, Dmytro, Fraumann, Simon G., Kreutz, Clemens, Zadora, Piotr K., Seyhan Agircan, Ayça, Konietzke, Philip, Engelmann, Theresa A., Hegermann, Jan, Mulugeta, Surafel, Kawabe, Hiroshi, Knudsen, Lars, Ochs, Matthias, Rotin, Daniela, Muley, Thomas, Kreuter, Michael, Herth, Felix J. F., Wielpütz, Mark O., Beers, Michael F., Klingmüller, Ursula, Mall, Marcus A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181726/ https://www.ncbi.nlm.nih.gov/pubmed/32332792 http://dx.doi.org/10.1038/s41467-020-15743-6

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