Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis

Gut microbial dysbiosis is associated with the development of autoimmune disease, but the mechanisms by which microbial dysbiosis affects the transition from asymptomatic autoimmunity to inflammatory disease are incompletely characterized. Here, we identify intestinal barrier integrity as an importa...

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Detalles Bibliográficos
Autores principales: Tajik, Narges, Frech, Michael, Schulz, Oscar, Schälter, Fabian, Lucas, Sébastien, Azizov, Vugar, Dürholz, Kerstin, Steffen, Franziska, Omata, Yasunori, Rings, Andreas, Bertog, Marko, Rizzo, Aroldo, Iljazovic, Aida, Basic, Marijana, Kleyer, Arnd, Culemann, Stephan, Krönke, Gerhard, Luo, Yubin, Überla, Klaus, Gaipl, Udo S., Frey, Benjamin, Strowig, Till, Sarter, Kerstin, Bischoff, Stephan C., Wirtz, Stefan, Cañete, Juan D., Ciccia, Francesco, Schett, Georg, Zaiss, Mario M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181728/
https://www.ncbi.nlm.nih.gov/pubmed/32332732
http://dx.doi.org/10.1038/s41467-020-15831-7

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