MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer

Transcriptional characterization and classification has potential to resolve the inter-tumor heterogeneity of colorectal cancer and improve patient management. Yet, robust transcriptional profiling is difficult using formalin-fixed, paraffin-embedded (FFPE) samples, which complicates testing in clin...

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Detalles Bibliográficos
Autores principales: Mattesen, Trine B., Rasmussen, Mads H., Sandoval, Juan, Ongen, Halit, Árnadóttir, Sigrid S., Gladov, Josephine, Martinez-Cardus, Anna, Castro de Moura, Manuel, Madsen, Anders H., Laurberg, Søren, Dermitzakis, Emmanouil T., Esteller, Manel, Andersen, Claus L., Bramsen, Jesper B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181739/
https://www.ncbi.nlm.nih.gov/pubmed/32332866
http://dx.doi.org/10.1038/s41467-020-16000-6

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