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DNA:RNA hybrids form at DNA double-strand breaks in transcriptionally active loci
The recent discovery of DNA:RNA hybrids, or R-loops, actively forming at DNA double-strand breaks (DSBs) has unlocked fresh insight into how RNA participates in DNA repair. However, the manner of DSB-induced R-loop formation is vital in determining its mechanism of action and is currently under deba...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181826/ https://www.ncbi.nlm.nih.gov/pubmed/32332801 http://dx.doi.org/10.1038/s41419-020-2464-6 |