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The UPR sensor IRE1α and the adenovirus E3-19K glycoprotein sustain persistent and lytic infections

Persistent viruses cause chronic disease, and threaten the lives of immunosuppressed individuals. Here, we elucidate a mechanism supporting the persistence of human adenovirus (AdV), a virus that can kill immunosuppressed patients. Cell biological analyses, genetics and chemical interference demonst...

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Detalles Bibliográficos
Autores principales:	Prasad, Vibhu, Suomalainen, Maarit, Jasiqi, Yllza, Hemmi, Silvio, Hearing, Patrick, Hosie, Louise, Burgert, Hans-Gerhard, Greber, Urs F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181865/ https://www.ncbi.nlm.nih.gov/pubmed/32332742 http://dx.doi.org/10.1038/s41467-020-15844-2

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