CtBP determines ovarian cancer cell fate through repression of death receptors

C-terminal binding protein 2 (CtBP2) is elevated in epithelial ovarian cancer, especially in the aggressive and highly lethal subtype, high-grade serous ovarian cancer (HGSOC). However, whether HGSOC tumor progression is dependent on CtBP2 or its paralog CtBP1, is not well understood. Here we report...

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Detalles Bibliográficos
Autores principales: Ding, Boxiao, Yuan, Fang, Damle, Priyadarshan K., Litovchick, Larisa, Drapkin, Ronny, Grossman, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181866/
https://www.ncbi.nlm.nih.gov/pubmed/32332713
http://dx.doi.org/10.1038/s41419-020-2455-7

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