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CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade

Multiple vaginal delivery (MVD) is an important factor for pelvic floor muscle (PFM) function decline and pelvic floor dysfunction (PFD). PFD is common in middle-aged and elderly women, but its pathogenesis is not clear. In this study, we found that the expression of CACNA1H was lower in the PFM of...

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Detalles Bibliográficos
Autores principales: Li, Suting, Hao, Menglei, Li, Bingshu, Chen, Mao, Chen, Jue, Tang, Jianming, Hong, Shasha, Min, Jie, Hu, Ming, Hong, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181873/
https://www.ncbi.nlm.nih.gov/pubmed/32332705
http://dx.doi.org/10.1038/s41419-020-2484-2