Genetic Characterization of Japanese Encephalitis Virus Genotype 5 Isolated from Patient, South Korea, 2015

We isolated Japanese encephalitis virus genotype 5 from human specimens in South Korea. Whole-genome analysis showed 90.4% identity with other genotype 5 viruses from humans. This virus had a unique insertion in the NS4A gene. However, the envelope protein contained Lys 84, which was specific to str...

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Autores principales: Woo, Jae Hoon, Jeong, Young Eui, Jo, Jung Eun, Shim, Sang-Mu, Ryou, Jungsang, Kim, Kyung-Chang, Lee, Won Ja, Lee, Joo-Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181942/
https://www.ncbi.nlm.nih.gov/pubmed/32310056
http://dx.doi.org/10.3201/eid2605.190977
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author Woo, Jae Hoon
Jeong, Young Eui
Jo, Jung Eun
Shim, Sang-Mu
Ryou, Jungsang
Kim, Kyung-Chang
Lee, Won Ja
Lee, Joo-Yeon
author_facet Woo, Jae Hoon
Jeong, Young Eui
Jo, Jung Eun
Shim, Sang-Mu
Ryou, Jungsang
Kim, Kyung-Chang
Lee, Won Ja
Lee, Joo-Yeon
author_sort Woo, Jae Hoon
collection PubMed
description We isolated Japanese encephalitis virus genotype 5 from human specimens in South Korea. Whole-genome analysis showed 90.4% identity with other genotype 5 viruses from humans. This virus had a unique insertion in the NS4A gene. However, the envelope protein contained Lys 84, which was specific to strains of genotype 5 viruses from South Korea.
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spelling pubmed-71819422020-05-06 Genetic Characterization of Japanese Encephalitis Virus Genotype 5 Isolated from Patient, South Korea, 2015 Woo, Jae Hoon Jeong, Young Eui Jo, Jung Eun Shim, Sang-Mu Ryou, Jungsang Kim, Kyung-Chang Lee, Won Ja Lee, Joo-Yeon Emerg Infect Dis Dispatch We isolated Japanese encephalitis virus genotype 5 from human specimens in South Korea. Whole-genome analysis showed 90.4% identity with other genotype 5 viruses from humans. This virus had a unique insertion in the NS4A gene. However, the envelope protein contained Lys 84, which was specific to strains of genotype 5 viruses from South Korea. Centers for Disease Control and Prevention 2020-05 /pmc/articles/PMC7181942/ /pubmed/32310056 http://dx.doi.org/10.3201/eid2605.190977 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Woo, Jae Hoon
Jeong, Young Eui
Jo, Jung Eun
Shim, Sang-Mu
Ryou, Jungsang
Kim, Kyung-Chang
Lee, Won Ja
Lee, Joo-Yeon
Genetic Characterization of Japanese Encephalitis Virus Genotype 5 Isolated from Patient, South Korea, 2015
title Genetic Characterization of Japanese Encephalitis Virus Genotype 5 Isolated from Patient, South Korea, 2015
title_full Genetic Characterization of Japanese Encephalitis Virus Genotype 5 Isolated from Patient, South Korea, 2015
title_fullStr Genetic Characterization of Japanese Encephalitis Virus Genotype 5 Isolated from Patient, South Korea, 2015
title_full_unstemmed Genetic Characterization of Japanese Encephalitis Virus Genotype 5 Isolated from Patient, South Korea, 2015
title_short Genetic Characterization of Japanese Encephalitis Virus Genotype 5 Isolated from Patient, South Korea, 2015
title_sort genetic characterization of japanese encephalitis virus genotype 5 isolated from patient, south korea, 2015
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181942/
https://www.ncbi.nlm.nih.gov/pubmed/32310056
http://dx.doi.org/10.3201/eid2605.190977
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