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Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development
Glioblastoma (GBM) is an aggressive type of brain cancer with a poor prognosis for affected patients. The current line of treatment only gives the patients a survival time of on average 15 months. In this work, we use genome-scale metabolic models (GEMs) together with other systems biology tools to...
Autores principales: | Larsson, Ida, Uhlén, Mathias, Zhang, Cheng, Mardinoglu, Adil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181968/ https://www.ncbi.nlm.nih.gov/pubmed/32362913 http://dx.doi.org/10.3389/fgene.2020.00381 |
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