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What do surgeons need to know about the digestive disorders and paraclinical abnormalities induced by COVID-19?

The symptoms associated with COVID-19 are mainly characterized by a triad composed of fever, dry cough and dyspnea. However, digestive symptoms have also been reported. At first considered as infrequent, they in fact seem to affect more than half of patients. The symptoms mainly include anorexia, di...

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Detalles Bibliográficos
Autores principales: Gornet, J.-M., Tran Minh, M.L., Leleu, F., Hassid, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181975/
https://www.ncbi.nlm.nih.gov/pubmed/32360205
http://dx.doi.org/10.1016/j.jviscsurg.2020.04.017
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author Gornet, J.-M.
Tran Minh, M.L.
Leleu, F.
Hassid, D.
author_facet Gornet, J.-M.
Tran Minh, M.L.
Leleu, F.
Hassid, D.
author_sort Gornet, J.-M.
collection PubMed
description The symptoms associated with COVID-19 are mainly characterized by a triad composed of fever, dry cough and dyspnea. However, digestive symptoms have also been reported. At first considered as infrequent, they in fact seem to affect more than half of patients. The symptoms mainly include anorexia, diarrhea, nausea and/or vomiting and abdominal pain. Even though prognosis is associated with lung injury, digestive symptoms seem significantly more frequent in patients presenting with severe COVID-19 infection. Digestive presentations, which may be isolated or which can precede pulmonary symptoms, have indeed been reported, with diarrhea as a leading clinical sign. The main biological abnormalities that can suggest COVID-19 infection at an early stage are lymphopenia, elevated CRP and heightened ASAT transaminases. Thoraco-abdominal scan seems useful as a means of on the one hand ruling out digestive pathology not connected with coronavirus and on the other hand searching for pulmonary images consistent with COVID-19 infection. No data exist on the value of digestive endoscopy in cases of persistent digestive symptoms. Moreover, the endoscopists may themselves be at significant risk of contamination. Fecal-oral transmission of the infection is possible, especially insofar as viral shedding in stools seems frequent and of longer duration than at the ENT level, including in patients with negative throat swab and without digestive symptoms. In some doubtful cases, virologic assessment of stool samples can yield definitive diagnosis. In the event of prolonged viral shedding in stools, a patient's persistent contagiousness is conceivable but not conclusively established. Upcoming serology should enable identification of the patients having been infected by the COVID-19 epidemic, particularly among previously undetected pauci-symptomatic members of a health care staff. Resumption of medico-surgical activity should be the object of a dedicated strategy preceding deconfinement.
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spelling pubmed-71819752020-04-27 What do surgeons need to know about the digestive disorders and paraclinical abnormalities induced by COVID-19? Gornet, J.-M. Tran Minh, M.L. Leleu, F. Hassid, D. J Visc Surg Article The symptoms associated with COVID-19 are mainly characterized by a triad composed of fever, dry cough and dyspnea. However, digestive symptoms have also been reported. At first considered as infrequent, they in fact seem to affect more than half of patients. The symptoms mainly include anorexia, diarrhea, nausea and/or vomiting and abdominal pain. Even though prognosis is associated with lung injury, digestive symptoms seem significantly more frequent in patients presenting with severe COVID-19 infection. Digestive presentations, which may be isolated or which can precede pulmonary symptoms, have indeed been reported, with diarrhea as a leading clinical sign. The main biological abnormalities that can suggest COVID-19 infection at an early stage are lymphopenia, elevated CRP and heightened ASAT transaminases. Thoraco-abdominal scan seems useful as a means of on the one hand ruling out digestive pathology not connected with coronavirus and on the other hand searching for pulmonary images consistent with COVID-19 infection. No data exist on the value of digestive endoscopy in cases of persistent digestive symptoms. Moreover, the endoscopists may themselves be at significant risk of contamination. Fecal-oral transmission of the infection is possible, especially insofar as viral shedding in stools seems frequent and of longer duration than at the ENT level, including in patients with negative throat swab and without digestive symptoms. In some doubtful cases, virologic assessment of stool samples can yield definitive diagnosis. In the event of prolonged viral shedding in stools, a patient's persistent contagiousness is conceivable but not conclusively established. Upcoming serology should enable identification of the patients having been infected by the COVID-19 epidemic, particularly among previously undetected pauci-symptomatic members of a health care staff. Resumption of medico-surgical activity should be the object of a dedicated strategy preceding deconfinement. Elsevier Masson SAS. 2020-06 2020-04-24 /pmc/articles/PMC7181975/ /pubmed/32360205 http://dx.doi.org/10.1016/j.jviscsurg.2020.04.017 Text en © 2020 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Gornet, J.-M.
Tran Minh, M.L.
Leleu, F.
Hassid, D.
What do surgeons need to know about the digestive disorders and paraclinical abnormalities induced by COVID-19?
title What do surgeons need to know about the digestive disorders and paraclinical abnormalities induced by COVID-19?
title_full What do surgeons need to know about the digestive disorders and paraclinical abnormalities induced by COVID-19?
title_fullStr What do surgeons need to know about the digestive disorders and paraclinical abnormalities induced by COVID-19?
title_full_unstemmed What do surgeons need to know about the digestive disorders and paraclinical abnormalities induced by COVID-19?
title_short What do surgeons need to know about the digestive disorders and paraclinical abnormalities induced by COVID-19?
title_sort what do surgeons need to know about the digestive disorders and paraclinical abnormalities induced by covid-19?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181975/
https://www.ncbi.nlm.nih.gov/pubmed/32360205
http://dx.doi.org/10.1016/j.jviscsurg.2020.04.017
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