Cargando…
Molecular Generation for Desired Transcriptome Changes With Adversarial Autoencoders
Gene expression profiles are useful for assessing the efficacy and side effects of drugs. In this paper, we propose a new generative model that infers drug molecules that could induce a desired change in gene expression. Our model—the Bidirectional Adversarial Autoencoder—explicitly separates cellul...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182000/ https://www.ncbi.nlm.nih.gov/pubmed/32362822 http://dx.doi.org/10.3389/fphar.2020.00269 |