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Management of hospital-acquired infections among patients hospitalized at Zewditu memorial hospital, Addis Ababa, Ethiopia: A prospective cross-sectional study

BACKGROUND: Hospital-Acquired Infections (HAIs) are acquired when the patient is hospitalized for more than 48 hours. In Ethiopia data are scarce in management appropriateness of HAIs. Hence, this study was aimed to assess the prevalence and management of HAIs among patients admitted at Zewditu Memo...

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Autores principales: Tassew, Segen Gebremeskel, Alebachew Woldu, Minyahil, Amogne Degu, Wondwossen, Shibeshi, Workineh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182178/
https://www.ncbi.nlm.nih.gov/pubmed/32330164
http://dx.doi.org/10.1371/journal.pone.0231949
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author Tassew, Segen Gebremeskel
Alebachew Woldu, Minyahil
Amogne Degu, Wondwossen
Shibeshi, Workineh
author_facet Tassew, Segen Gebremeskel
Alebachew Woldu, Minyahil
Amogne Degu, Wondwossen
Shibeshi, Workineh
author_sort Tassew, Segen Gebremeskel
collection PubMed
description BACKGROUND: Hospital-Acquired Infections (HAIs) are acquired when the patient is hospitalized for more than 48 hours. In Ethiopia data are scarce in management appropriateness of HAIs. Hence, this study was aimed to assess the prevalence and management of HAIs among patients admitted at Zewditu Memorial Hospital. METHOD: A facility based prospective cross sectional study was conducted from March 1, 2017 to August 30, 2017. The sample was proportionally allocated among (medical, pediatrics, gynecology and obstetrics and surgical) wards, based on patient flow. Data were collected using data abstraction format and supplemented by key informant interview. Interview was made on eight physicians and four microbiologists who have been working in the wards during study period. Management appropriateness was assessed using Infectious Disease Society of America guideline and experts opinion (Infectious disease specialist). A multivariate logistic regression was used to identify factors associated with HAIs. RESULT: The prevalence of HAIs was 19.8%. Surgical Site Infection (SSI) and pneumonia accounted for 20 (24.7%) of the infections. Culture and sensitivity was done for 24 (29.6%) patients. Of the 81 patients who developed HAIs, 54 (66.67%) of them were treated inappropriately. Physicians’ response for this variation was information gap, forgetfulness, affordability and availability issue of first line medications. Younger age (AOR (Adjusted odds ratio) = 8.53, 95% CI: 2.67–27.30); male gender (AOR = 2.06, 95% CI: 1.01–4.22); longer hospital stay (AOR = 0.17, 95% CI: 0.06–0.51); and previous hospital admission (AOR = 3.22, 95% CI: 1.76–5.89); were independent predictors of HAIs. CONCLUSION: Prevalence of HAIs and inappropriate management were substantially high in this study. Pneumonia and SSI were the common types of HAIs. Locally conformable guidelines could help to correct such problems.
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spelling pubmed-71821782020-05-05 Management of hospital-acquired infections among patients hospitalized at Zewditu memorial hospital, Addis Ababa, Ethiopia: A prospective cross-sectional study Tassew, Segen Gebremeskel Alebachew Woldu, Minyahil Amogne Degu, Wondwossen Shibeshi, Workineh PLoS One Research Article BACKGROUND: Hospital-Acquired Infections (HAIs) are acquired when the patient is hospitalized for more than 48 hours. In Ethiopia data are scarce in management appropriateness of HAIs. Hence, this study was aimed to assess the prevalence and management of HAIs among patients admitted at Zewditu Memorial Hospital. METHOD: A facility based prospective cross sectional study was conducted from March 1, 2017 to August 30, 2017. The sample was proportionally allocated among (medical, pediatrics, gynecology and obstetrics and surgical) wards, based on patient flow. Data were collected using data abstraction format and supplemented by key informant interview. Interview was made on eight physicians and four microbiologists who have been working in the wards during study period. Management appropriateness was assessed using Infectious Disease Society of America guideline and experts opinion (Infectious disease specialist). A multivariate logistic regression was used to identify factors associated with HAIs. RESULT: The prevalence of HAIs was 19.8%. Surgical Site Infection (SSI) and pneumonia accounted for 20 (24.7%) of the infections. Culture and sensitivity was done for 24 (29.6%) patients. Of the 81 patients who developed HAIs, 54 (66.67%) of them were treated inappropriately. Physicians’ response for this variation was information gap, forgetfulness, affordability and availability issue of first line medications. Younger age (AOR (Adjusted odds ratio) = 8.53, 95% CI: 2.67–27.30); male gender (AOR = 2.06, 95% CI: 1.01–4.22); longer hospital stay (AOR = 0.17, 95% CI: 0.06–0.51); and previous hospital admission (AOR = 3.22, 95% CI: 1.76–5.89); were independent predictors of HAIs. CONCLUSION: Prevalence of HAIs and inappropriate management were substantially high in this study. Pneumonia and SSI were the common types of HAIs. Locally conformable guidelines could help to correct such problems. Public Library of Science 2020-04-24 /pmc/articles/PMC7182178/ /pubmed/32330164 http://dx.doi.org/10.1371/journal.pone.0231949 Text en © 2020 Tassew et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Tassew, Segen Gebremeskel
Alebachew Woldu, Minyahil
Amogne Degu, Wondwossen
Shibeshi, Workineh
Management of hospital-acquired infections among patients hospitalized at Zewditu memorial hospital, Addis Ababa, Ethiopia: A prospective cross-sectional study
title Management of hospital-acquired infections among patients hospitalized at Zewditu memorial hospital, Addis Ababa, Ethiopia: A prospective cross-sectional study
title_full Management of hospital-acquired infections among patients hospitalized at Zewditu memorial hospital, Addis Ababa, Ethiopia: A prospective cross-sectional study
title_fullStr Management of hospital-acquired infections among patients hospitalized at Zewditu memorial hospital, Addis Ababa, Ethiopia: A prospective cross-sectional study
title_full_unstemmed Management of hospital-acquired infections among patients hospitalized at Zewditu memorial hospital, Addis Ababa, Ethiopia: A prospective cross-sectional study
title_short Management of hospital-acquired infections among patients hospitalized at Zewditu memorial hospital, Addis Ababa, Ethiopia: A prospective cross-sectional study
title_sort management of hospital-acquired infections among patients hospitalized at zewditu memorial hospital, addis ababa, ethiopia: a prospective cross-sectional study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182178/
https://www.ncbi.nlm.nih.gov/pubmed/32330164
http://dx.doi.org/10.1371/journal.pone.0231949
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