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SLC6A14, a Na(+)/Cl(−)-coupled amino acid transporter, functions as a tumor promoter in colon and is a target for Wnt signaling
SLC6A14 is a Na(+)/Cl(−)-coupled transporter for neutral and cationic amino acids. It is expressed at basal levels in the normal colon but is up-regulated in colon cancer. However, the relevance of this up-regulation to cancer progression and the mechanisms involved in the up-regulation remain unkno...
Autores principales: | Sikder, Mohd O. F., Sivaprakasam, Sathish, Brown, Timothy P., Thangaraju, Muthusamy, Bhutia, Yangzom D., Ganapathy, Vadivel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182441/ https://www.ncbi.nlm.nih.gov/pubmed/32219372 http://dx.doi.org/10.1042/BCJ20200099 |
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