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A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells
Protein interactions guide the majority of cellular processes. Orthogonal hetero-specific protein-protein interaction domains may facilitate better control of engineered biological systems. Here, we report a tunable de novo designed set of orthogonal coiled-coil (CC) peptide heterodimers (the NICP s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182445/ https://www.ncbi.nlm.nih.gov/pubmed/31907374 http://dx.doi.org/10.1038/s41589-019-0443-y |