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Acute Complications of Diabetes and its Predictors among Adult Diabetic Patients at Jimma Medical Center, Southwest Ethiopia

BACKGROUND: Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia resulting from impairment in insulin secretion, insulin action, or both. It is responsible for a wide range of acute and chronic complications. In this study, we aimed to assess acute complications of...

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Autores principales: Negera, Getandale Zeleke, Weldegebriel, Belachew, Fekadu, Ginenus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182448/
https://www.ncbi.nlm.nih.gov/pubmed/32368116
http://dx.doi.org/10.2147/DMSO.S249163
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author Negera, Getandale Zeleke
Weldegebriel, Belachew
Fekadu, Ginenus
author_facet Negera, Getandale Zeleke
Weldegebriel, Belachew
Fekadu, Ginenus
author_sort Negera, Getandale Zeleke
collection PubMed
description BACKGROUND: Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia resulting from impairment in insulin secretion, insulin action, or both. It is responsible for a wide range of acute and chronic complications. In this study, we aimed to assess acute complications of diabetes and its predictors among adult DM patients at Jimma Medical Center (JMC), southwest Ethiopia. METHODS: A facility-based cross-sectional study involving 348 diabetic patients was conducted from February to May 31, 2019 at JMC. Logistic regression was conducted to identify predictors of acute complications of diabetes. Variables with P≤0.25 on bivariate logistic regression were considered candidates for multivariate regression. ORs and 95% CIs  with P<0.05 were considered statistically significant. RESULTS: Of the 348 patients, 225 (64.7%) were male, and the mean age of study participants was 46±15.5 years. Most (281, 80.7%) had type 2 DM. More than two-thirds (240, 69%)had diabetes duration of <5 years. During the study period, 92 (26.4%) patients developed acute complications of diabetes. Of these, 68 (73.9%) had diabetic ketoacidosis, 21 (22.8%) a hyperglycemic hyperosmolar state, and three (3.3%) hypoglycemia. Presence of comorbidity (AOR 5.6, 95% CI 2.80–11.19), type 1 DM (AOR 9.3, 95% CI 4.36–19.82), uncontrolled blood glucose (AOR 1.91, 95% CI 1.05–3.45), and lack of access to a health facility within a reasonable distance (AOR 1.96, 95% CI 1.11–3.45) were independent predictors of acute complications of diabetes. CONCLUSION: The magnitude of acute complications among DM patients at JMC was high. Comorbidity, type 1 DM, uncontrolled blood sugar, and lack of access to a health facility within a reasonable distance were independent predictors of acute complications. Clinicians should follow up this subgroup of DM patients closely.
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spelling pubmed-71824482020-05-04 Acute Complications of Diabetes and its Predictors among Adult Diabetic Patients at Jimma Medical Center, Southwest Ethiopia Negera, Getandale Zeleke Weldegebriel, Belachew Fekadu, Ginenus Diabetes Metab Syndr Obes Original Research BACKGROUND: Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia resulting from impairment in insulin secretion, insulin action, or both. It is responsible for a wide range of acute and chronic complications. In this study, we aimed to assess acute complications of diabetes and its predictors among adult DM patients at Jimma Medical Center (JMC), southwest Ethiopia. METHODS: A facility-based cross-sectional study involving 348 diabetic patients was conducted from February to May 31, 2019 at JMC. Logistic regression was conducted to identify predictors of acute complications of diabetes. Variables with P≤0.25 on bivariate logistic regression were considered candidates for multivariate regression. ORs and 95% CIs  with P<0.05 were considered statistically significant. RESULTS: Of the 348 patients, 225 (64.7%) were male, and the mean age of study participants was 46±15.5 years. Most (281, 80.7%) had type 2 DM. More than two-thirds (240, 69%)had diabetes duration of <5 years. During the study period, 92 (26.4%) patients developed acute complications of diabetes. Of these, 68 (73.9%) had diabetic ketoacidosis, 21 (22.8%) a hyperglycemic hyperosmolar state, and three (3.3%) hypoglycemia. Presence of comorbidity (AOR 5.6, 95% CI 2.80–11.19), type 1 DM (AOR 9.3, 95% CI 4.36–19.82), uncontrolled blood glucose (AOR 1.91, 95% CI 1.05–3.45), and lack of access to a health facility within a reasonable distance (AOR 1.96, 95% CI 1.11–3.45) were independent predictors of acute complications of diabetes. CONCLUSION: The magnitude of acute complications among DM patients at JMC was high. Comorbidity, type 1 DM, uncontrolled blood sugar, and lack of access to a health facility within a reasonable distance were independent predictors of acute complications. Clinicians should follow up this subgroup of DM patients closely. Dove 2020-04-20 /pmc/articles/PMC7182448/ /pubmed/32368116 http://dx.doi.org/10.2147/DMSO.S249163 Text en © 2020 Negera et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Negera, Getandale Zeleke
Weldegebriel, Belachew
Fekadu, Ginenus
Acute Complications of Diabetes and its Predictors among Adult Diabetic Patients at Jimma Medical Center, Southwest Ethiopia
title Acute Complications of Diabetes and its Predictors among Adult Diabetic Patients at Jimma Medical Center, Southwest Ethiopia
title_full Acute Complications of Diabetes and its Predictors among Adult Diabetic Patients at Jimma Medical Center, Southwest Ethiopia
title_fullStr Acute Complications of Diabetes and its Predictors among Adult Diabetic Patients at Jimma Medical Center, Southwest Ethiopia
title_full_unstemmed Acute Complications of Diabetes and its Predictors among Adult Diabetic Patients at Jimma Medical Center, Southwest Ethiopia
title_short Acute Complications of Diabetes and its Predictors among Adult Diabetic Patients at Jimma Medical Center, Southwest Ethiopia
title_sort acute complications of diabetes and its predictors among adult diabetic patients at jimma medical center, southwest ethiopia
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182448/
https://www.ncbi.nlm.nih.gov/pubmed/32368116
http://dx.doi.org/10.2147/DMSO.S249163
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