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Targeting PIK3CG in Combination with Paclitaxel as a Potential Therapeutic Regimen in Claudin-Low Breast Cancer
PURPOSE: Molecular targeting is a powerful approach for aggressive claudin-low breast cancer (CLBC). Overexpression of PI3K catalytic subunit gamma (PIK3CG) in human CLBC is offering a promising opportunity for targeted therapies. We utilized a specific inhibitor of PIK3CG combined with paclitaxel (...
Autores principales: | Chang, Jun, Hong, Ling, Liu, Yaozhong, Pan, Yiwen, Yang, Hao, Ye, Wenrui, Xu, Keli, Li, Zhijian, Zhang, Shubing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182462/ https://www.ncbi.nlm.nih.gov/pubmed/32368142 http://dx.doi.org/10.2147/CMAR.S250171 |
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