Cargando…
Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara
The Major Histocompatibility Complex (MHC), as a family of highly polymorphic genes associated with immunity in the genome of the vertebrate, has become an important indicator for assessing the evolutionary potential of wildlife. In order to better protect Zootoca vivipara in the Greater Khingan Ran...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182658/ https://www.ncbi.nlm.nih.gov/pubmed/32285916 http://dx.doi.org/10.1042/BSR20193809 |
_version_ | 1783526272549257216 |
---|---|
author | Liu, Wanli Liu, Yufen Liu, Peng Zhao, Wenge |
author_facet | Liu, Wanli Liu, Yufen Liu, Peng Zhao, Wenge |
author_sort | Liu, Wanli |
collection | PubMed |
description | The Major Histocompatibility Complex (MHC), as a family of highly polymorphic genes associated with immunity in the genome of the vertebrate, has become an important indicator for assessing the evolutionary potential of wildlife. In order to better protect Zootoca vivipara in the Greater Khingan Range and Lesser Khingan Range, to understand the genetic structure of Z. vivipara, and to explore the mechanism and phylogenetic relationship of the gene polymorphisms, the MHC molecular marker method was used to analyze Z. vivipara population. Forty-seven alleles were obtained from four populations. The four populations were highly polymorphic, rich in genetic information, and had significant genetic diversity. There were certain inbreeding phenomena. There was a high degree of genetic differentiation among populations, which was caused by genetic drift and natural selection. The sequence undergoes genetic duplication and recombination. The existence of trans-species polymorphism was found in the constructed phylogenetic tree. The present study provides a theoretical basis for species protection of Z. vivipara. |
format | Online Article Text |
id | pubmed-7182658 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Portland Press Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71826582020-05-05 Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara Liu, Wanli Liu, Yufen Liu, Peng Zhao, Wenge Biosci Rep Zoology & Marine Biology The Major Histocompatibility Complex (MHC), as a family of highly polymorphic genes associated with immunity in the genome of the vertebrate, has become an important indicator for assessing the evolutionary potential of wildlife. In order to better protect Zootoca vivipara in the Greater Khingan Range and Lesser Khingan Range, to understand the genetic structure of Z. vivipara, and to explore the mechanism and phylogenetic relationship of the gene polymorphisms, the MHC molecular marker method was used to analyze Z. vivipara population. Forty-seven alleles were obtained from four populations. The four populations were highly polymorphic, rich in genetic information, and had significant genetic diversity. There were certain inbreeding phenomena. There was a high degree of genetic differentiation among populations, which was caused by genetic drift and natural selection. The sequence undergoes genetic duplication and recombination. The existence of trans-species polymorphism was found in the constructed phylogenetic tree. The present study provides a theoretical basis for species protection of Z. vivipara. Portland Press Ltd. 2020-04-24 /pmc/articles/PMC7182658/ /pubmed/32285916 http://dx.doi.org/10.1042/BSR20193809 Text en © 2020 The Author(s). https://creativecommons.org/licenses/by/4.0/ This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY). |
spellingShingle | Zoology & Marine Biology Liu, Wanli Liu, Yufen Liu, Peng Zhao, Wenge Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara |
title | Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara |
title_full | Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara |
title_fullStr | Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara |
title_full_unstemmed | Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara |
title_short | Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara |
title_sort | genetic diversity of major histocompatibility complex class i genes in zootoca vivipara |
topic | Zoology & Marine Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182658/ https://www.ncbi.nlm.nih.gov/pubmed/32285916 http://dx.doi.org/10.1042/BSR20193809 |
work_keys_str_mv | AT liuwanli geneticdiversityofmajorhistocompatibilitycomplexclassigenesinzootocavivipara AT liuyufen geneticdiversityofmajorhistocompatibilitycomplexclassigenesinzootocavivipara AT liupeng geneticdiversityofmajorhistocompatibilitycomplexclassigenesinzootocavivipara AT zhaowenge geneticdiversityofmajorhistocompatibilitycomplexclassigenesinzootocavivipara |