Cargando…

Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara

The Major Histocompatibility Complex (MHC), as a family of highly polymorphic genes associated with immunity in the genome of the vertebrate, has become an important indicator for assessing the evolutionary potential of wildlife. In order to better protect Zootoca vivipara in the Greater Khingan Ran...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Wanli, Liu, Yufen, Liu, Peng, Zhao, Wenge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182658/
https://www.ncbi.nlm.nih.gov/pubmed/32285916
http://dx.doi.org/10.1042/BSR20193809
_version_ 1783526272549257216
author Liu, Wanli
Liu, Yufen
Liu, Peng
Zhao, Wenge
author_facet Liu, Wanli
Liu, Yufen
Liu, Peng
Zhao, Wenge
author_sort Liu, Wanli
collection PubMed
description The Major Histocompatibility Complex (MHC), as a family of highly polymorphic genes associated with immunity in the genome of the vertebrate, has become an important indicator for assessing the evolutionary potential of wildlife. In order to better protect Zootoca vivipara in the Greater Khingan Range and Lesser Khingan Range, to understand the genetic structure of Z. vivipara, and to explore the mechanism and phylogenetic relationship of the gene polymorphisms, the MHC molecular marker method was used to analyze Z. vivipara population. Forty-seven alleles were obtained from four populations. The four populations were highly polymorphic, rich in genetic information, and had significant genetic diversity. There were certain inbreeding phenomena. There was a high degree of genetic differentiation among populations, which was caused by genetic drift and natural selection. The sequence undergoes genetic duplication and recombination. The existence of trans-species polymorphism was found in the constructed phylogenetic tree. The present study provides a theoretical basis for species protection of Z. vivipara.
format Online
Article
Text
id pubmed-7182658
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Portland Press Ltd.
record_format MEDLINE/PubMed
spelling pubmed-71826582020-05-05 Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara Liu, Wanli Liu, Yufen Liu, Peng Zhao, Wenge Biosci Rep Zoology & Marine Biology The Major Histocompatibility Complex (MHC), as a family of highly polymorphic genes associated with immunity in the genome of the vertebrate, has become an important indicator for assessing the evolutionary potential of wildlife. In order to better protect Zootoca vivipara in the Greater Khingan Range and Lesser Khingan Range, to understand the genetic structure of Z. vivipara, and to explore the mechanism and phylogenetic relationship of the gene polymorphisms, the MHC molecular marker method was used to analyze Z. vivipara population. Forty-seven alleles were obtained from four populations. The four populations were highly polymorphic, rich in genetic information, and had significant genetic diversity. There were certain inbreeding phenomena. There was a high degree of genetic differentiation among populations, which was caused by genetic drift and natural selection. The sequence undergoes genetic duplication and recombination. The existence of trans-species polymorphism was found in the constructed phylogenetic tree. The present study provides a theoretical basis for species protection of Z. vivipara. Portland Press Ltd. 2020-04-24 /pmc/articles/PMC7182658/ /pubmed/32285916 http://dx.doi.org/10.1042/BSR20193809 Text en © 2020 The Author(s). https://creativecommons.org/licenses/by/4.0/ This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY).
spellingShingle Zoology & Marine Biology
Liu, Wanli
Liu, Yufen
Liu, Peng
Zhao, Wenge
Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara
title Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara
title_full Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara
title_fullStr Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara
title_full_unstemmed Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara
title_short Genetic diversity of major histocompatibility complex class I genes in Zootoca vivipara
title_sort genetic diversity of major histocompatibility complex class i genes in zootoca vivipara
topic Zoology & Marine Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182658/
https://www.ncbi.nlm.nih.gov/pubmed/32285916
http://dx.doi.org/10.1042/BSR20193809
work_keys_str_mv AT liuwanli geneticdiversityofmajorhistocompatibilitycomplexclassigenesinzootocavivipara
AT liuyufen geneticdiversityofmajorhistocompatibilitycomplexclassigenesinzootocavivipara
AT liupeng geneticdiversityofmajorhistocompatibilitycomplexclassigenesinzootocavivipara
AT zhaowenge geneticdiversityofmajorhistocompatibilitycomplexclassigenesinzootocavivipara