Association of Oral Anticoagulants and Verapamil or Diltiazem With Adverse Bleeding Events in Patients With Nonvalvular Atrial Fibrillation and Normal Kidney Function

IMPORTANCE: Direct oral anticoagulants (DOACs) are purported to have fewer drug-drug interactions than warfarin. However, potential interactions with coprescribed medications are still a safety concern. Verapamil hydrochloride and diltiazem hydrochloride are combined P-glycoprotein (P-gp) and CYP3A4...

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Detalles Bibliográficos
Autores principales: Pham, Phuong, Schmidt, Stephan, Lesko, Lawrence, Lip, Gregory Y. H., Brown, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182798/
https://www.ncbi.nlm.nih.gov/pubmed/32329770
http://dx.doi.org/10.1001/jamanetworkopen.2020.3593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182798/
https://www.ncbi.nlm.nih.gov/pubmed/32329770
http://dx.doi.org/10.1001/jamanetworkopen.2020.3593

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