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Facile Fabrication of Microfluidic Chips for 3D Hydrodynamic Focusing and Wet Spinning of Polymeric Fibers
Microfluidic wet spinning has gained increasing interest in recent years as an alternative to conventional wet spinning by offering higher control in fiber morphology and a gateway for the development of multi-material fibers. Conventionally, microfluidic chips used to create such fibers are fabrica...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182802/ https://www.ncbi.nlm.nih.gov/pubmed/32164361 http://dx.doi.org/10.3390/polym12030633 |
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author | Gursoy, Akin Iranshahi, Kamran Wei, Kongchang Tello, Alexis Armagan, Efe Boesel, Luciano F. Sorin, Fabien Rossi, René M. Defraeye, Thijs Toncelli, Claudio |
author_facet | Gursoy, Akin Iranshahi, Kamran Wei, Kongchang Tello, Alexis Armagan, Efe Boesel, Luciano F. Sorin, Fabien Rossi, René M. Defraeye, Thijs Toncelli, Claudio |
author_sort | Gursoy, Akin |
collection | PubMed |
description | Microfluidic wet spinning has gained increasing interest in recent years as an alternative to conventional wet spinning by offering higher control in fiber morphology and a gateway for the development of multi-material fibers. Conventionally, microfluidic chips used to create such fibers are fabricated by soft lithography, a method that requires both time and investment in necessary cleanroom facilities. Recently, additive manufacturing techniques were investigated for rapid and cost-efficient prototyping. However, these microfluidic devices are not yet matching the resolutions and tolerances offered by soft lithography. Herein, we report a facile and rapid method using selected arrays of hypodermic needles as templates within a silicone elastomer matrix. The produced microfluidic spinnerets display co-axially aligned circular channels. By simulation and flow experiments, we prove that these devices can maintain laminar flow conditions and achieve precise 3D hydrodynamic focusing. The devices were tested with a commercial polyurethane formulation to demonstrate that fibers with desired morphologies can be produced by varying the degree of hydrodynamic focusing. Thanks to the adaptability of this concept to different microfluidic spinneret designs—as well as to its transparency, ease of fabrication, and cost-efficient procedure—this device sets the ground for transferring microfluidic wet spinning towards industrial textile settings. |
format | Online Article Text |
id | pubmed-7182802 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71828022020-05-01 Facile Fabrication of Microfluidic Chips for 3D Hydrodynamic Focusing and Wet Spinning of Polymeric Fibers Gursoy, Akin Iranshahi, Kamran Wei, Kongchang Tello, Alexis Armagan, Efe Boesel, Luciano F. Sorin, Fabien Rossi, René M. Defraeye, Thijs Toncelli, Claudio Polymers (Basel) Article Microfluidic wet spinning has gained increasing interest in recent years as an alternative to conventional wet spinning by offering higher control in fiber morphology and a gateway for the development of multi-material fibers. Conventionally, microfluidic chips used to create such fibers are fabricated by soft lithography, a method that requires both time and investment in necessary cleanroom facilities. Recently, additive manufacturing techniques were investigated for rapid and cost-efficient prototyping. However, these microfluidic devices are not yet matching the resolutions and tolerances offered by soft lithography. Herein, we report a facile and rapid method using selected arrays of hypodermic needles as templates within a silicone elastomer matrix. The produced microfluidic spinnerets display co-axially aligned circular channels. By simulation and flow experiments, we prove that these devices can maintain laminar flow conditions and achieve precise 3D hydrodynamic focusing. The devices were tested with a commercial polyurethane formulation to demonstrate that fibers with desired morphologies can be produced by varying the degree of hydrodynamic focusing. Thanks to the adaptability of this concept to different microfluidic spinneret designs—as well as to its transparency, ease of fabrication, and cost-efficient procedure—this device sets the ground for transferring microfluidic wet spinning towards industrial textile settings. MDPI 2020-03-10 /pmc/articles/PMC7182802/ /pubmed/32164361 http://dx.doi.org/10.3390/polym12030633 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Gursoy, Akin Iranshahi, Kamran Wei, Kongchang Tello, Alexis Armagan, Efe Boesel, Luciano F. Sorin, Fabien Rossi, René M. Defraeye, Thijs Toncelli, Claudio Facile Fabrication of Microfluidic Chips for 3D Hydrodynamic Focusing and Wet Spinning of Polymeric Fibers |
title | Facile Fabrication of Microfluidic Chips for 3D Hydrodynamic Focusing and Wet Spinning of Polymeric Fibers |
title_full | Facile Fabrication of Microfluidic Chips for 3D Hydrodynamic Focusing and Wet Spinning of Polymeric Fibers |
title_fullStr | Facile Fabrication of Microfluidic Chips for 3D Hydrodynamic Focusing and Wet Spinning of Polymeric Fibers |
title_full_unstemmed | Facile Fabrication of Microfluidic Chips for 3D Hydrodynamic Focusing and Wet Spinning of Polymeric Fibers |
title_short | Facile Fabrication of Microfluidic Chips for 3D Hydrodynamic Focusing and Wet Spinning of Polymeric Fibers |
title_sort | facile fabrication of microfluidic chips for 3d hydrodynamic focusing and wet spinning of polymeric fibers |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182802/ https://www.ncbi.nlm.nih.gov/pubmed/32164361 http://dx.doi.org/10.3390/polym12030633 |
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