Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome

Netherton syndrome (NS) is a monogenic skin disease resulting from loss of function of lymphoepithelial Kazal-type-related protease inhibitor (LEKTI-1). In this study we examine if bacteria residing on the skin are influenced by the loss of LEKTI-1 and if interaction between this human gene and resi...

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Detalles Bibliográficos
Autores principales: Williams, Michael R., Cau, Laura, Wang, Yichen, Kaul, Drishti, Sanford, James A., Zaramela, Livia S., Khalil, Shadi, Butcher, Anna M., Zengler, Karsten, Horswill, Alexander R., Dupont, Christopher L., Hovnanian, Alain, Gallo, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183042/
https://www.ncbi.nlm.nih.gov/pubmed/32130897
http://dx.doi.org/10.1016/j.celrep.2020.02.021

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