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Combined proinflammatory cytokine and cognate activation of invariant natural killer T cells enhances anti-DNA antibody responses

Invariant natural killer T (iNKT) cells serve as early rapid responders in the innate immune response to self-derived autoantigens and pathogen-derived danger signals and antigens. iNKT cells can serve both as helpers for effector B cells and negatively regulate autoreactive B cells. Specifically, i...

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Detalles Bibliográficos
Autores principales: Sedimbi, Saikiran K., Hägglöf, Thomas, Garimella, Manasa G., Wang, Shan, Duhlin, Amanda, Coelho, Ana, Ingelshed, Katrine, Mondoc, Emma, Malin, Stephen G., Holmdahl, Rikard, Lane, David P., Leadbetter, Elizabeth A., Karlsson, Mikael C. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183147/
https://www.ncbi.nlm.nih.gov/pubmed/32295878
http://dx.doi.org/10.1073/pnas.1920463117