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Adverse maternal environment and western diet impairs cognitive function and alters hippocampal glucocorticoid receptor promoter methylation in male mice

Adverse maternal environment (AME) and high‐fat diet in early childhood increase the risk of cognitive impairment and depression later in life. Cognitive impairment associates with hippocampal dysfunction. A key regulator of hippocampal function is the glucocorticoid receptor. Increased hippocampal...

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Detalles Bibliográficos
Autores principales: Ke, Xingrao, Fu, Qi, Sterrett, Jennifer, Hillard, Cecilia J., Lane, Robert H., Majnik, Amber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183239/
https://www.ncbi.nlm.nih.gov/pubmed/32333646
http://dx.doi.org/10.14814/phy2.14407