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A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis
Information is lacking on the clinical impact of the novel coronavirus, SARS-CoV-2, on people with cystic fibrosis (CF). Our aim was to characterise SARS-CoV-2 infection in people with cystic fibrosis. Methods: Anonymised data submitted by each participating country to their National CF Registry was...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183287/ https://www.ncbi.nlm.nih.gov/pubmed/32376098 http://dx.doi.org/10.1016/j.jcf.2020.04.012 |
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author | Cosgriff, Rebecca Ahern, Susannah Bell, Scott C. Brownlee, Keith Burgel, Pierre-Régis Byrnes, Cass Corvol, Harriet Cheng, Stephanie Y. Elbert, Alexander Faro, Albert Goss, Christopher H. Gulmans, Vincent Marshall, Bruce C. McKone, Edward Middleton, Peter G. Ruseckaite, Rasa Stephenson, Anne L. Carr, Siobhán B |
author_facet | Cosgriff, Rebecca Ahern, Susannah Bell, Scott C. Brownlee, Keith Burgel, Pierre-Régis Byrnes, Cass Corvol, Harriet Cheng, Stephanie Y. Elbert, Alexander Faro, Albert Goss, Christopher H. Gulmans, Vincent Marshall, Bruce C. McKone, Edward Middleton, Peter G. Ruseckaite, Rasa Stephenson, Anne L. Carr, Siobhán B |
author_sort | Cosgriff, Rebecca |
collection | PubMed |
description | Information is lacking on the clinical impact of the novel coronavirus, SARS-CoV-2, on people with cystic fibrosis (CF). Our aim was to characterise SARS-CoV-2 infection in people with cystic fibrosis. Methods: Anonymised data submitted by each participating country to their National CF Registry was reported using a standardised template, then collated and summarised. Results: 40 cases have been reported across 8 countries. Of the 40 cases, 31 (78%) were symptomatic for SARS-CoV-2 at presentation, with 24 (60%) having a fever. 70% have recovered, 30% remain unresolved at time of reporting, and no deaths have been submitted. Conclusions: This early report shows good recovery from SARS-CoV-2 in this heterogeneous CF cohort. The disease course does not seem to differ from the general population, but the current numbers are too small to draw firm conclusions and people with CF should continue to strictly follow public health advice to protect themselves from infection. |
format | Online Article Text |
id | pubmed-7183287 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Authors. Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71832872020-04-27 A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis Cosgriff, Rebecca Ahern, Susannah Bell, Scott C. Brownlee, Keith Burgel, Pierre-Régis Byrnes, Cass Corvol, Harriet Cheng, Stephanie Y. Elbert, Alexander Faro, Albert Goss, Christopher H. Gulmans, Vincent Marshall, Bruce C. McKone, Edward Middleton, Peter G. Ruseckaite, Rasa Stephenson, Anne L. Carr, Siobhán B J Cyst Fibros Article Information is lacking on the clinical impact of the novel coronavirus, SARS-CoV-2, on people with cystic fibrosis (CF). Our aim was to characterise SARS-CoV-2 infection in people with cystic fibrosis. Methods: Anonymised data submitted by each participating country to their National CF Registry was reported using a standardised template, then collated and summarised. Results: 40 cases have been reported across 8 countries. Of the 40 cases, 31 (78%) were symptomatic for SARS-CoV-2 at presentation, with 24 (60%) having a fever. 70% have recovered, 30% remain unresolved at time of reporting, and no deaths have been submitted. Conclusions: This early report shows good recovery from SARS-CoV-2 in this heterogeneous CF cohort. The disease course does not seem to differ from the general population, but the current numbers are too small to draw firm conclusions and people with CF should continue to strictly follow public health advice to protect themselves from infection. The Authors. Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society. 2020-05 2020-04-25 /pmc/articles/PMC7183287/ /pubmed/32376098 http://dx.doi.org/10.1016/j.jcf.2020.04.012 Text en © 2020 The Authors. Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Cosgriff, Rebecca Ahern, Susannah Bell, Scott C. Brownlee, Keith Burgel, Pierre-Régis Byrnes, Cass Corvol, Harriet Cheng, Stephanie Y. Elbert, Alexander Faro, Albert Goss, Christopher H. Gulmans, Vincent Marshall, Bruce C. McKone, Edward Middleton, Peter G. Ruseckaite, Rasa Stephenson, Anne L. Carr, Siobhán B A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis |
title | A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis |
title_full | A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis |
title_fullStr | A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis |
title_full_unstemmed | A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis |
title_short | A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis |
title_sort | multinational report to characterise sars-cov-2 infection in people with cystic fibrosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183287/ https://www.ncbi.nlm.nih.gov/pubmed/32376098 http://dx.doi.org/10.1016/j.jcf.2020.04.012 |
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