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Regulation of pancreatic cancer TRAIL resistance by protein O-GlcNAcylation
TRAIL-activating therapy is promising in treating various cancers, including pancreatic cancer, a highly malignant neoplasm with poor prognosis. However, many pancreatic cancer cells are resistant to TRAIL-induced apoptosis despite their expression of intact death receptors (DRs). Protein O-GlcNAcyl...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183418/ https://www.ncbi.nlm.nih.gov/pubmed/31896813 http://dx.doi.org/10.1038/s41374-019-0365-z |