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Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance

Priming at the site of natural infection typically elicits a protective T cell response against subsequent pathogen encounter. Here, we report the identification of a novel fungal antigen that we harnessed for mucosal vaccination and tetramer generation to test whether we can elicit protective, anti...

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Detalles Bibliográficos
Autores principales: Dobson, Hannah E., Dias, Lucas Dos Santos, Kohn, Elaine M., Fites, Scott, Wiesner, Darin L., Dileepan, Thamotharampillai, Kujoth, Gregory C., Abraham, Ambily, Ostroff, Gary R., Klein, Bruce S., Wüthrich, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183437/
https://www.ncbi.nlm.nih.gov/pubmed/31900406
http://dx.doi.org/10.1038/s41385-019-0244-3