SARS-CoV-2 in the ocular surface of COVID-19 patients

The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surface swabs...

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Autores principales: Xie, Hua-Tao, Jiang, Shi-Yun, Xu, Kang-Kang, Liu, Xin, Xu, Bing, Wang, Lin, Zhang, Ming-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183451/
https://www.ncbi.nlm.nih.gov/pubmed/32355863
http://dx.doi.org/10.1186/s40662-020-00189-0
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author Xie, Hua-Tao
Jiang, Shi-Yun
Xu, Kang-Kang
Liu, Xin
Xu, Bing
Wang, Lin
Zhang, Ming-Chang
author_facet Xie, Hua-Tao
Jiang, Shi-Yun
Xu, Kang-Kang
Liu, Xin
Xu, Bing
Wang, Lin
Zhang, Ming-Chang
author_sort Xie, Hua-Tao
collection PubMed
description The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surface swabs collected for virus detection. RNA was detected strong positive in samples of both eyes from two patients. Therefore, SARS-CoV-2 may exist in the normal ocular surface of COVID-19 patients, suggesting that this virus might be spread through conjunctival contact.
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spelling pubmed-71834512020-04-27 SARS-CoV-2 in the ocular surface of COVID-19 patients Xie, Hua-Tao Jiang, Shi-Yun Xu, Kang-Kang Liu, Xin Xu, Bing Wang, Lin Zhang, Ming-Chang Eye Vis (Lond) Short Report The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surface swabs collected for virus detection. RNA was detected strong positive in samples of both eyes from two patients. Therefore, SARS-CoV-2 may exist in the normal ocular surface of COVID-19 patients, suggesting that this virus might be spread through conjunctival contact. BioMed Central 2020-04-26 /pmc/articles/PMC7183451/ /pubmed/32355863 http://dx.doi.org/10.1186/s40662-020-00189-0 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Short Report
Xie, Hua-Tao
Jiang, Shi-Yun
Xu, Kang-Kang
Liu, Xin
Xu, Bing
Wang, Lin
Zhang, Ming-Chang
SARS-CoV-2 in the ocular surface of COVID-19 patients
title SARS-CoV-2 in the ocular surface of COVID-19 patients
title_full SARS-CoV-2 in the ocular surface of COVID-19 patients
title_fullStr SARS-CoV-2 in the ocular surface of COVID-19 patients
title_full_unstemmed SARS-CoV-2 in the ocular surface of COVID-19 patients
title_short SARS-CoV-2 in the ocular surface of COVID-19 patients
title_sort sars-cov-2 in the ocular surface of covid-19 patients
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183451/
https://www.ncbi.nlm.nih.gov/pubmed/32355863
http://dx.doi.org/10.1186/s40662-020-00189-0
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