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Variability of serum reproductive hormones in cows presenting various reproductive conditions in semi-arid areas of the North West Province, South Africa

BACKGROUND AND AIM: Hormones play a significant role in supporting reproductive processes. Predisposition to metabolic disorders may result from biological alterations in the neurohormonal system, thus leading to impaired immune function and poor reproductive performance. The aim of this study was t...

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Autores principales: Molefe, K., Mwanza, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183473/
https://www.ncbi.nlm.nih.gov/pubmed/32367956
http://dx.doi.org/10.14202/vetworld.2020.502-507
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author Molefe, K.
Mwanza, M.
author_facet Molefe, K.
Mwanza, M.
author_sort Molefe, K.
collection PubMed
description BACKGROUND AND AIM: Hormones play a significant role in supporting reproductive processes. Predisposition to metabolic disorders may result from biological alterations in the neurohormonal system, thus leading to impaired immune function and poor reproductive performance. The aim of this study was to determine the reproductive hormonal profile in cows with reproductive conditions in semi-arid areas of the North West Province, South Africa, to establish possible correlations between different conditions and the hormonal profile. MATERIALS AND METHODS: Blood samples were collected from cows in different communal areas of Mafikeng. Convenience sampling was used to collect samples for the study. Blood samples were collected cows experiencing dystocia (n=50), retained placenta (n=13), downer cow syndrome (n=34), vaginal prolapse (n=16), and abortions (n=69), following cases reported at the Animal Health Hospital of the North-West University, Mafikeng Campus. Descriptive statistics, such as mean and standard deviations, were used to describe the distribution of hormone levels across reproductive conditions. p-value less than the significance level was set at 5% (p<0.05). RESULTS: Data obtained revealed significantly higher estradiol in abortion (1122.99±71.99 pg/ml), downer cow syndrome (781.32±135.7 pg/ml), and dystocia (862.09±123.44 pg/ml). Oxytocin (OT) differed significantly in cows with dystocia (370.50±71.66 pg/ml) and abortion (574.73±60.65 pg/ml). Significantly low progesterone (Pg) was observed in abortion (2.45±1.509 ng/ml) and dystocia (8.59±0.402 ng/ml) while increased prostaglandin alpha was observed in cows with vaginal prolapse and abortion. CONCLUSION: The findings highlight an increase in serum estradiol and OT in aborting cows. Low Pg and estradiol in cows with vaginal prolapses and retained placenta were noted. An association was seen between downer cow syndrome and high concentrations of estradiol and Pg. Prostaglandin alpha may increase in cases of vaginal prolapse and abortion. Hormonal alterations were observed and may contribute to the incidences of different reproductive conditions.
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spelling pubmed-71834732020-05-04 Variability of serum reproductive hormones in cows presenting various reproductive conditions in semi-arid areas of the North West Province, South Africa Molefe, K. Mwanza, M. Vet World Research Article BACKGROUND AND AIM: Hormones play a significant role in supporting reproductive processes. Predisposition to metabolic disorders may result from biological alterations in the neurohormonal system, thus leading to impaired immune function and poor reproductive performance. The aim of this study was to determine the reproductive hormonal profile in cows with reproductive conditions in semi-arid areas of the North West Province, South Africa, to establish possible correlations between different conditions and the hormonal profile. MATERIALS AND METHODS: Blood samples were collected from cows in different communal areas of Mafikeng. Convenience sampling was used to collect samples for the study. Blood samples were collected cows experiencing dystocia (n=50), retained placenta (n=13), downer cow syndrome (n=34), vaginal prolapse (n=16), and abortions (n=69), following cases reported at the Animal Health Hospital of the North-West University, Mafikeng Campus. Descriptive statistics, such as mean and standard deviations, were used to describe the distribution of hormone levels across reproductive conditions. p-value less than the significance level was set at 5% (p<0.05). RESULTS: Data obtained revealed significantly higher estradiol in abortion (1122.99±71.99 pg/ml), downer cow syndrome (781.32±135.7 pg/ml), and dystocia (862.09±123.44 pg/ml). Oxytocin (OT) differed significantly in cows with dystocia (370.50±71.66 pg/ml) and abortion (574.73±60.65 pg/ml). Significantly low progesterone (Pg) was observed in abortion (2.45±1.509 ng/ml) and dystocia (8.59±0.402 ng/ml) while increased prostaglandin alpha was observed in cows with vaginal prolapse and abortion. CONCLUSION: The findings highlight an increase in serum estradiol and OT in aborting cows. Low Pg and estradiol in cows with vaginal prolapses and retained placenta were noted. An association was seen between downer cow syndrome and high concentrations of estradiol and Pg. Prostaglandin alpha may increase in cases of vaginal prolapse and abortion. Hormonal alterations were observed and may contribute to the incidences of different reproductive conditions. Veterinary World 2020-03 2020-03-17 /pmc/articles/PMC7183473/ /pubmed/32367956 http://dx.doi.org/10.14202/vetworld.2020.502-507 Text en Copyright: © Molefe and Mwanza. http://creativecommons.org/licenses/by/4.0 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Molefe, K.
Mwanza, M.
Variability of serum reproductive hormones in cows presenting various reproductive conditions in semi-arid areas of the North West Province, South Africa
title Variability of serum reproductive hormones in cows presenting various reproductive conditions in semi-arid areas of the North West Province, South Africa
title_full Variability of serum reproductive hormones in cows presenting various reproductive conditions in semi-arid areas of the North West Province, South Africa
title_fullStr Variability of serum reproductive hormones in cows presenting various reproductive conditions in semi-arid areas of the North West Province, South Africa
title_full_unstemmed Variability of serum reproductive hormones in cows presenting various reproductive conditions in semi-arid areas of the North West Province, South Africa
title_short Variability of serum reproductive hormones in cows presenting various reproductive conditions in semi-arid areas of the North West Province, South Africa
title_sort variability of serum reproductive hormones in cows presenting various reproductive conditions in semi-arid areas of the north west province, south africa
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183473/
https://www.ncbi.nlm.nih.gov/pubmed/32367956
http://dx.doi.org/10.14202/vetworld.2020.502-507
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