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Mixed 20-peptide cancer vaccine in combination with docetaxel and dexamethasone for castration-resistant prostate cancer: a randomized phase II trial
A novel cancer vaccine consisting of 20 mixed peptides (KRM-20) was designed to induce cytotoxic T lymphocytes (CTL) against twelve different tumor-associated antigens. The aim of this phase II trial was to examine whether KRM-20 in combination with docetaxel and dexamethasone enhances the antitumor...
Autores principales: | Noguchi, Masanori, Arai, Gaku, Egawa, Shin, Ohyama, Chikara, Naito, Seiji, Matsumoto, Kazumasa, Uemura, Hirotsugu, Nakagawa, Masayuki, Nasu, Yasutomo, Eto, Masatoshi, Suekane, Shigetaka, Sasada, Tetsuro, Shichijo, Shigeki, Yamada, Akira, Kakuma, Tatsuyuki, Itoh, Kyogo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183507/ https://www.ncbi.nlm.nih.gov/pubmed/32025848 http://dx.doi.org/10.1007/s00262-020-02498-8 |
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