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Viral metagenomics revealed diverse CRESS-DNA virus genomes in faeces of forest musk deer

BACKGROUND: Musk deer can produce musk which has high medicinal value and is closely related to human health. Viruses in forest musk deer both threaten the health of forest musk deer and human beings. METHODS: Using viral metagenomics we investigated the virome in 85 faeces samples collected from fo...

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Autores principales: Liu, Qi, Wang, Hao, Ling, Yu, Yang, Shi-Xing, Wang, Xiao-Chun, Zhou, Rui, Xiao, Yu-Qing, Chen, Xu, Yang, Jie, Fu, Wei-Guo, Zhang, Wen, Qi, Gui-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183601/
https://www.ncbi.nlm.nih.gov/pubmed/32334626
http://dx.doi.org/10.1186/s12985-020-01332-y
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author Liu, Qi
Wang, Hao
Ling, Yu
Yang, Shi-Xing
Wang, Xiao-Chun
Zhou, Rui
Xiao, Yu-Qing
Chen, Xu
Yang, Jie
Fu, Wei-Guo
Zhang, Wen
Qi, Gui-Lan
author_facet Liu, Qi
Wang, Hao
Ling, Yu
Yang, Shi-Xing
Wang, Xiao-Chun
Zhou, Rui
Xiao, Yu-Qing
Chen, Xu
Yang, Jie
Fu, Wei-Guo
Zhang, Wen
Qi, Gui-Lan
author_sort Liu, Qi
collection PubMed
description BACKGROUND: Musk deer can produce musk which has high medicinal value and is closely related to human health. Viruses in forest musk deer both threaten the health of forest musk deer and human beings. METHODS: Using viral metagenomics we investigated the virome in 85 faeces samples collected from forest musk deer. RESULTS: In this article, eight novel CRESS-DNA viruses were characterized, whole genomes were 2148 nt–3852 nt in length. Phylogenetic analysis indicated that some viral genomes were part of four different groups of CRESS-DNA virus belonging in the unclassified CRESS-DNA virus, Smacoviridae, pCPa-like virus and pPAPh2-like virus. UJSL001 (MN621482), UJSL003 (MN621469) and UJSL017 (MN621476) fall into the branch of unclassified CRESS-DNA virus (CRESSV1–2), UJSL002 (MN621468), UJSL004 (MN621481) and UJSL007 (MN621470) belong to the cluster of Smacoviridae, UJSL005 (MN604398) showing close relationship with pCPa-like (pCRESS4–8) clusters and UJSL006 (MN621480) clustered into the branch of pPAPh2-like (pCRESS9) virus, respectively. CONCLUSION: The virome in faeces samples of forest musk deer from Chengdu, Sichuan province, China was revealed, which further characterized the diversity of viruses in forest musk deer intestinal tract.
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spelling pubmed-71836012020-04-29 Viral metagenomics revealed diverse CRESS-DNA virus genomes in faeces of forest musk deer Liu, Qi Wang, Hao Ling, Yu Yang, Shi-Xing Wang, Xiao-Chun Zhou, Rui Xiao, Yu-Qing Chen, Xu Yang, Jie Fu, Wei-Guo Zhang, Wen Qi, Gui-Lan Virol J Research BACKGROUND: Musk deer can produce musk which has high medicinal value and is closely related to human health. Viruses in forest musk deer both threaten the health of forest musk deer and human beings. METHODS: Using viral metagenomics we investigated the virome in 85 faeces samples collected from forest musk deer. RESULTS: In this article, eight novel CRESS-DNA viruses were characterized, whole genomes were 2148 nt–3852 nt in length. Phylogenetic analysis indicated that some viral genomes were part of four different groups of CRESS-DNA virus belonging in the unclassified CRESS-DNA virus, Smacoviridae, pCPa-like virus and pPAPh2-like virus. UJSL001 (MN621482), UJSL003 (MN621469) and UJSL017 (MN621476) fall into the branch of unclassified CRESS-DNA virus (CRESSV1–2), UJSL002 (MN621468), UJSL004 (MN621481) and UJSL007 (MN621470) belong to the cluster of Smacoviridae, UJSL005 (MN604398) showing close relationship with pCPa-like (pCRESS4–8) clusters and UJSL006 (MN621480) clustered into the branch of pPAPh2-like (pCRESS9) virus, respectively. CONCLUSION: The virome in faeces samples of forest musk deer from Chengdu, Sichuan province, China was revealed, which further characterized the diversity of viruses in forest musk deer intestinal tract. BioMed Central 2020-04-25 /pmc/articles/PMC7183601/ /pubmed/32334626 http://dx.doi.org/10.1186/s12985-020-01332-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Liu, Qi
Wang, Hao
Ling, Yu
Yang, Shi-Xing
Wang, Xiao-Chun
Zhou, Rui
Xiao, Yu-Qing
Chen, Xu
Yang, Jie
Fu, Wei-Guo
Zhang, Wen
Qi, Gui-Lan
Viral metagenomics revealed diverse CRESS-DNA virus genomes in faeces of forest musk deer
title Viral metagenomics revealed diverse CRESS-DNA virus genomes in faeces of forest musk deer
title_full Viral metagenomics revealed diverse CRESS-DNA virus genomes in faeces of forest musk deer
title_fullStr Viral metagenomics revealed diverse CRESS-DNA virus genomes in faeces of forest musk deer
title_full_unstemmed Viral metagenomics revealed diverse CRESS-DNA virus genomes in faeces of forest musk deer
title_short Viral metagenomics revealed diverse CRESS-DNA virus genomes in faeces of forest musk deer
title_sort viral metagenomics revealed diverse cress-dna virus genomes in faeces of forest musk deer
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183601/
https://www.ncbi.nlm.nih.gov/pubmed/32334626
http://dx.doi.org/10.1186/s12985-020-01332-y
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