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Sickle cell disease and malaria: decreased exposure and asplenia can modulate the risk from Plasmodium falciparum
BACKGROUND: Patients with sickle cell disease (SCD), an inherited haemoglobinopathy, have increased risk of malaria, at least in part due to impaired splenic function. Infection with Plasmodium falciparum in SCD patients can trigger painful vaso-occlusive crisis, increase the severity of anaemia, an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183641/ https://www.ncbi.nlm.nih.gov/pubmed/32334583 http://dx.doi.org/10.1186/s12936-020-03212-w |