Sickle cell disease and malaria: decreased exposure and asplenia can modulate the risk from Plasmodium falciparum

BACKGROUND: Patients with sickle cell disease (SCD), an inherited haemoglobinopathy, have increased risk of malaria, at least in part due to impaired splenic function. Infection with Plasmodium falciparum in SCD patients can trigger painful vaso-occlusive crisis, increase the severity of anaemia, an...

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Detalles Bibliográficos
Autores principales: Mwaiswelo, Richard O., Mawala, William, Iversen, Per O., de Montalembert, Mariane, Luzzatto, Lucio, Makani, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183641/
https://www.ncbi.nlm.nih.gov/pubmed/32334583
http://dx.doi.org/10.1186/s12936-020-03212-w

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