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Relationship of endoscopic lesions of the renal papilla with type of renal stone and 24 h urine analysis
BACKGROUND: Our purpose was to study the relationship of the 3 different types of endoscopic calcifications of the renal papilla (Randall’s plaque, intratubular calcification, papillary crater) with the type of stone and urine analysis. METHODS: This prospective study examined 41 patients (age range...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183647/ https://www.ncbi.nlm.nih.gov/pubmed/32334600 http://dx.doi.org/10.1186/s12894-020-00615-4 |
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author | Sabaté Arroyo, X.A. Grases Freixedas, F. Bauzà Quetglas, J. L. Guimerà Garcia, J. Pieras Ayala, E. |
author_facet | Sabaté Arroyo, X.A. Grases Freixedas, F. Bauzà Quetglas, J. L. Guimerà Garcia, J. Pieras Ayala, E. |
author_sort | Sabaté Arroyo, X.A. |
collection | PubMed |
description | BACKGROUND: Our purpose was to study the relationship of the 3 different types of endoscopic calcifications of the renal papilla (Randall’s plaque, intratubular calcification, papillary crater) with the type of stone and urine analysis. METHODS: This prospective study examined 41 patients (age range: 18 to 80 years) who received retrograde intrarenal surgery (RIRS) for renal lithiasis (mean stone size: 15.3 ± 7.2 mm). The renal papilla injuries were endoscopically classified as Randall’s plaque, intratubular calcification, or papillary crater. Calculi were classified as uric acid, calcium oxalate monohydrate (COM; papillary and cavity), calcium oxalate dihydrate (COD), or calcium phosphate (CP). A 24 h urine analysis of calcium, oxalate, citrate, phosphate, and pH was performed in all patients. The relationship of each type of papillary injury with type of stone and urine chemistry was determined. Fisher’s exact test and Student’s t-test were used to determine the significance of relationships, and a p value below 0.05 was considered significant. RESULTS: The most common injury was tubular calcification (78%), followed by Randall’s plaque (58%), and papillary crater (39%). There was no significant relationship of Randall’s plaque with type of stone. However, endoscopic intratubular calcification (p = 0.025) and papillary crater (p = 0.041) were more common in patients with COD and CP stones. There were also significant relationships of papillary crater with hypercalciuria (p = 0.036) and hyperoxaluria (p = 0.024), and of Randall’s plaque with hypocitraturia (p = 0.005). CONCLUSIONS: There are certain specific relationships between the different types of papillary calcifications that were endoscopically detected with stone chemistry and urine analysis. COD and CP stones were associated with endoscopic tubular calcifications and papillary craters. Hypercalciuria was associated with tubular calcification, and hypocitraturia was associated with Randall’s plaque. |
format | Online Article Text |
id | pubmed-7183647 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-71836472020-04-29 Relationship of endoscopic lesions of the renal papilla with type of renal stone and 24 h urine analysis Sabaté Arroyo, X.A. Grases Freixedas, F. Bauzà Quetglas, J. L. Guimerà Garcia, J. Pieras Ayala, E. BMC Urol Research Article BACKGROUND: Our purpose was to study the relationship of the 3 different types of endoscopic calcifications of the renal papilla (Randall’s plaque, intratubular calcification, papillary crater) with the type of stone and urine analysis. METHODS: This prospective study examined 41 patients (age range: 18 to 80 years) who received retrograde intrarenal surgery (RIRS) for renal lithiasis (mean stone size: 15.3 ± 7.2 mm). The renal papilla injuries were endoscopically classified as Randall’s plaque, intratubular calcification, or papillary crater. Calculi were classified as uric acid, calcium oxalate monohydrate (COM; papillary and cavity), calcium oxalate dihydrate (COD), or calcium phosphate (CP). A 24 h urine analysis of calcium, oxalate, citrate, phosphate, and pH was performed in all patients. The relationship of each type of papillary injury with type of stone and urine chemistry was determined. Fisher’s exact test and Student’s t-test were used to determine the significance of relationships, and a p value below 0.05 was considered significant. RESULTS: The most common injury was tubular calcification (78%), followed by Randall’s plaque (58%), and papillary crater (39%). There was no significant relationship of Randall’s plaque with type of stone. However, endoscopic intratubular calcification (p = 0.025) and papillary crater (p = 0.041) were more common in patients with COD and CP stones. There were also significant relationships of papillary crater with hypercalciuria (p = 0.036) and hyperoxaluria (p = 0.024), and of Randall’s plaque with hypocitraturia (p = 0.005). CONCLUSIONS: There are certain specific relationships between the different types of papillary calcifications that were endoscopically detected with stone chemistry and urine analysis. COD and CP stones were associated with endoscopic tubular calcifications and papillary craters. Hypercalciuria was associated with tubular calcification, and hypocitraturia was associated with Randall’s plaque. BioMed Central 2020-04-25 /pmc/articles/PMC7183647/ /pubmed/32334600 http://dx.doi.org/10.1186/s12894-020-00615-4 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Sabaté Arroyo, X.A. Grases Freixedas, F. Bauzà Quetglas, J. L. Guimerà Garcia, J. Pieras Ayala, E. Relationship of endoscopic lesions of the renal papilla with type of renal stone and 24 h urine analysis |
title | Relationship of endoscopic lesions of the renal papilla with type of renal stone and 24 h urine analysis |
title_full | Relationship of endoscopic lesions of the renal papilla with type of renal stone and 24 h urine analysis |
title_fullStr | Relationship of endoscopic lesions of the renal papilla with type of renal stone and 24 h urine analysis |
title_full_unstemmed | Relationship of endoscopic lesions of the renal papilla with type of renal stone and 24 h urine analysis |
title_short | Relationship of endoscopic lesions of the renal papilla with type of renal stone and 24 h urine analysis |
title_sort | relationship of endoscopic lesions of the renal papilla with type of renal stone and 24 h urine analysis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7183647/ https://www.ncbi.nlm.nih.gov/pubmed/32334600 http://dx.doi.org/10.1186/s12894-020-00615-4 |
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