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Long-Term Clinical Outcomes of Cardiac Surgery for Kidney Transplant Patients

Purpose: Immunosuppressant and steroid are inevitable for graft survival after renal transplantation, and their usage is known to be a risk factor for mortality and morbidity after cardiac surgery. We evaluated the long-term clinical outcomes in patients who underwent cardiac surgery after renal tra...

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Autores principales: Komagamine, Masahide, Nishinaka, Tomohiro, Ichihara, Yuki, Saito, Satoshi, Niinami, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184036/
https://www.ncbi.nlm.nih.gov/pubmed/31447456
http://dx.doi.org/10.5761/atcs.oa.19-00192
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author Komagamine, Masahide
Nishinaka, Tomohiro
Ichihara, Yuki
Saito, Satoshi
Niinami, Hiroshi
author_facet Komagamine, Masahide
Nishinaka, Tomohiro
Ichihara, Yuki
Saito, Satoshi
Niinami, Hiroshi
author_sort Komagamine, Masahide
collection PubMed
description Purpose: Immunosuppressant and steroid are inevitable for graft survival after renal transplantation, and their usage is known to be a risk factor for mortality and morbidity after cardiac surgery. We evaluated the long-term clinical outcomes in patients who underwent cardiac surgery after renal transplantation. Methods: We retrospectively reviewed 23 patients who underwent cardiac surgery after renal transplantation with maintained grafts at the time of the cardiac surgery in our institution between June 2000 and June 2018 (19 males, 4 females; mean age, 55 (38–81) years). Results: The interval from renal transplantation to cardiac surgery was 80.0 ± 84.6 (0.25–298) months. The mean follow-up period after cardiac surgery was 78.3 (range: 1–216) months. Cumulative survival rates at 1, 5, 7, and 10 years were 95.7%, 95.7%, 87.7%, and 68.2%, respectively. Renal graft survival rates at 1 and 5 years were 86.1% and 79.9%, respectively. Conclusions: This retrospective review suggests that cardiac surgery in kidney transplant patients can result in good survival rates. Thanks to dedicated postoperative and long-term management, approximately 80% of the renal grafts still maintained their function 5 years after cardiac surgery.
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spelling pubmed-71840362020-04-27 Long-Term Clinical Outcomes of Cardiac Surgery for Kidney Transplant Patients Komagamine, Masahide Nishinaka, Tomohiro Ichihara, Yuki Saito, Satoshi Niinami, Hiroshi Ann Thorac Cardiovasc Surg Original Article Purpose: Immunosuppressant and steroid are inevitable for graft survival after renal transplantation, and their usage is known to be a risk factor for mortality and morbidity after cardiac surgery. We evaluated the long-term clinical outcomes in patients who underwent cardiac surgery after renal transplantation. Methods: We retrospectively reviewed 23 patients who underwent cardiac surgery after renal transplantation with maintained grafts at the time of the cardiac surgery in our institution between June 2000 and June 2018 (19 males, 4 females; mean age, 55 (38–81) years). Results: The interval from renal transplantation to cardiac surgery was 80.0 ± 84.6 (0.25–298) months. The mean follow-up period after cardiac surgery was 78.3 (range: 1–216) months. Cumulative survival rates at 1, 5, 7, and 10 years were 95.7%, 95.7%, 87.7%, and 68.2%, respectively. Renal graft survival rates at 1 and 5 years were 86.1% and 79.9%, respectively. Conclusions: This retrospective review suggests that cardiac surgery in kidney transplant patients can result in good survival rates. Thanks to dedicated postoperative and long-term management, approximately 80% of the renal grafts still maintained their function 5 years after cardiac surgery. The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery 2019-08-26 2020 /pmc/articles/PMC7184036/ /pubmed/31447456 http://dx.doi.org/10.5761/atcs.oa.19-00192 Text en ©2020 Annals of Thoracic and Cardiovascular Surgery http://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NonDerivatives International License (http://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Article
Komagamine, Masahide
Nishinaka, Tomohiro
Ichihara, Yuki
Saito, Satoshi
Niinami, Hiroshi
Long-Term Clinical Outcomes of Cardiac Surgery for Kidney Transplant Patients
title Long-Term Clinical Outcomes of Cardiac Surgery for Kidney Transplant Patients
title_full Long-Term Clinical Outcomes of Cardiac Surgery for Kidney Transplant Patients
title_fullStr Long-Term Clinical Outcomes of Cardiac Surgery for Kidney Transplant Patients
title_full_unstemmed Long-Term Clinical Outcomes of Cardiac Surgery for Kidney Transplant Patients
title_short Long-Term Clinical Outcomes of Cardiac Surgery for Kidney Transplant Patients
title_sort long-term clinical outcomes of cardiac surgery for kidney transplant patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184036/
https://www.ncbi.nlm.nih.gov/pubmed/31447456
http://dx.doi.org/10.5761/atcs.oa.19-00192
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