Clinical Utility of Diffusion-weighted Whole-body Magnetic Resonance Imaging with Background Body Signal Suppression for Assessing and Monitoring IgG4-related Disease

A 77-year-old man with symptoms of chest pain was diagnosed with immunoglobulin G4 (IgG4)-related disease. Fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) revealed an intense uptake in the submandibular gland, lymph nodes and abdominal aortic wall. Diffusion-weighted...

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Autores principales: Oshita, Akira, Kono, Yusuke, Miyoshi, Toru, Suzuki, Moeko, Kazatani, Takuro, Matsuoka, Hiroshi, Kawakami, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184072/
https://www.ncbi.nlm.nih.gov/pubmed/31787698
http://dx.doi.org/10.2169/internalmedicine.3712-19
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author Oshita, Akira
Kono, Yusuke
Miyoshi, Toru
Suzuki, Moeko
Kazatani, Takuro
Matsuoka, Hiroshi
Kawakami, Hideo
author_facet Oshita, Akira
Kono, Yusuke
Miyoshi, Toru
Suzuki, Moeko
Kazatani, Takuro
Matsuoka, Hiroshi
Kawakami, Hideo
author_sort Oshita, Akira
collection PubMed
description A 77-year-old man with symptoms of chest pain was diagnosed with immunoglobulin G4 (IgG4)-related disease. Fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) revealed an intense uptake in the submandibular gland, lymph nodes and abdominal aortic wall. Diffusion-weighted imaging with background body signal suppression (DWIBS) revealed signal enhancements at the same location as those of the FDG-PET/CT findings. The DWIBS signal intensity decreased after steroid treatment, so we decreased the steroid dosage. Relapse did not occur. DWIBS makes it possible to adjust the medicine dosage while confirming the therapeutic effects and will likely be a useful method for monitoring IgG4-related disease.
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spelling pubmed-71840722020-04-29 Clinical Utility of Diffusion-weighted Whole-body Magnetic Resonance Imaging with Background Body Signal Suppression for Assessing and Monitoring IgG4-related Disease Oshita, Akira Kono, Yusuke Miyoshi, Toru Suzuki, Moeko Kazatani, Takuro Matsuoka, Hiroshi Kawakami, Hideo Intern Med Case Report A 77-year-old man with symptoms of chest pain was diagnosed with immunoglobulin G4 (IgG4)-related disease. Fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) revealed an intense uptake in the submandibular gland, lymph nodes and abdominal aortic wall. Diffusion-weighted imaging with background body signal suppression (DWIBS) revealed signal enhancements at the same location as those of the FDG-PET/CT findings. The DWIBS signal intensity decreased after steroid treatment, so we decreased the steroid dosage. Relapse did not occur. DWIBS makes it possible to adjust the medicine dosage while confirming the therapeutic effects and will likely be a useful method for monitoring IgG4-related disease. The Japanese Society of Internal Medicine 2019-11-29 2020-04-01 /pmc/articles/PMC7184072/ /pubmed/31787698 http://dx.doi.org/10.2169/internalmedicine.3712-19 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Oshita, Akira
Kono, Yusuke
Miyoshi, Toru
Suzuki, Moeko
Kazatani, Takuro
Matsuoka, Hiroshi
Kawakami, Hideo
Clinical Utility of Diffusion-weighted Whole-body Magnetic Resonance Imaging with Background Body Signal Suppression for Assessing and Monitoring IgG4-related Disease
title Clinical Utility of Diffusion-weighted Whole-body Magnetic Resonance Imaging with Background Body Signal Suppression for Assessing and Monitoring IgG4-related Disease
title_full Clinical Utility of Diffusion-weighted Whole-body Magnetic Resonance Imaging with Background Body Signal Suppression for Assessing and Monitoring IgG4-related Disease
title_fullStr Clinical Utility of Diffusion-weighted Whole-body Magnetic Resonance Imaging with Background Body Signal Suppression for Assessing and Monitoring IgG4-related Disease
title_full_unstemmed Clinical Utility of Diffusion-weighted Whole-body Magnetic Resonance Imaging with Background Body Signal Suppression for Assessing and Monitoring IgG4-related Disease
title_short Clinical Utility of Diffusion-weighted Whole-body Magnetic Resonance Imaging with Background Body Signal Suppression for Assessing and Monitoring IgG4-related Disease
title_sort clinical utility of diffusion-weighted whole-body magnetic resonance imaging with background body signal suppression for assessing and monitoring igg4-related disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184072/
https://www.ncbi.nlm.nih.gov/pubmed/31787698
http://dx.doi.org/10.2169/internalmedicine.3712-19
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