Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy

BACKGROUND: Mouse models of mild spinal muscular atrophy (SMA) have been extremely challenging to generate. This paucity of model systems has limited our understanding of pathophysiological events in milder forms of the disease and of the effect of SMN depletion during aging. METHODS: A mild mouse m...

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Detalles Bibliográficos
Autores principales: Deguise, Marc-Olivier, De Repentigny, Yves, Tierney, Alexandra, Beauvais, Ariane, Michaud, Jean, Chehade, Lucia, Thabet, Mohamed, Paul, Brittany, Reilly, Aoife, Gagnon, Sabrina, Renaud, Jean-Marc, Kothary, Rashmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184161/
https://www.ncbi.nlm.nih.gov/pubmed/32339936
http://dx.doi.org/10.1016/j.ebiom.2020.102750

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