DNA Barcoding in Nonhuman Primates Reveals Important Limitations in Retrovirus Integration Site Analysis

In vivo tracking of retrovirus-tagged blood stem and progenitor cells is used to study hematopoiesis. Two techniques are used most frequently: sequencing the locus of retrovirus insertion, termed integration site analysis, or retrovirus DNA barcode sequencing. Of these, integration site analysis is...

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Detalles Bibliográficos
Autores principales: Adair, Jennifer E., Enstrom, Mark R., Haworth, Kevin G., Schefter, Lauren E., Shahbazi, Reza, Humphrys, Daniel R., Porter, Shaina, Tam, Kenric, Porteus, Matthew H., Kiem, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184234/
https://www.ncbi.nlm.nih.gov/pubmed/32355868
http://dx.doi.org/10.1016/j.omtm.2020.03.021

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