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Characterizing pancreatic β-cell heterogeneity in the streptozotocin model by single-cell transcriptomic analysis

OBJECTIVES: The streptozotocin (STZ) model is widely used in diabetes research. However, the cellular and molecular states of pancreatic endocrine cells in this model remain unclear. This study explored the molecular characteristics of islet cells treated with STZ and re-evaluated β-cell dysfunction...

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Detalles Bibliográficos
Autores principales:	Feng, Ye, Qiu, Wei-Lin, Yu, Xin-Xin, Zhang, Yu, He, Mao-Yang, Li, Lin-Chen, Yang, Li, Zhang, Weiyi, Franti, Michael, Ye, Junqing, Hoeck, Joerg D., Xu, Cheng-Ran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184252/ https://www.ncbi.nlm.nih.gov/pubmed/32247924 http://dx.doi.org/10.1016/j.molmet.2020.100982

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