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The H2B ubiquitin-protein ligase RNF40 is required for somatic cell reprogramming
Direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) requires a resetting of the epigenome in order to facilitate a cell fate transition. Previous studies have shown that epigenetic modifying enzymes play a central role in controlling induced pluripotency and the generatio...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184622/ https://www.ncbi.nlm.nih.gov/pubmed/32341358 http://dx.doi.org/10.1038/s41419-020-2482-4 |