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Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase

Diet is a major source of human exposure to polycyclic aromatic hydrocarbons (PAHs), of which benzo[a]pyrene (BaP) is the most commonly studied and measured. BaP has been considered to exert its genotoxic effects after metabolic activation by cytochrome P450 (CYP) enzymes whose activity can be modul...

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Detalles Bibliográficos
Autores principales:	Reed, Lindsay, Jarvis, Ian W.H., Phillips, David H., Arlt, Volker M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184669/ https://www.ncbi.nlm.nih.gov/pubmed/32265041 http://dx.doi.org/10.1016/j.mrgentox.2020.503162

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