Cargando…

Epigenetic regulation in human cancer: the potential role of epi-drug in cancer therapy

Epigenetics is dynamic and heritable modifications to the genome that occur independently of DNA sequence. It requires interactions cohesively with various enzymes and other molecular components. Aberrant epigenetic alterations can lead to inappropriate onset of genetic expressions and promote tumor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Yuanjun, Chan, Yau-Tuen, Tan, Hor-Yue, Li, Sha, Wang, Ning, Feng, Yibin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184703/ https://www.ncbi.nlm.nih.gov/pubmed/32340605 http://dx.doi.org/10.1186/s12943-020-01197-3

Ejemplares similares

CRISPR-Cas9 library screening approach for anti-cancer drug discovery: overview and perspectives
por: Chan, Yau-Tuen, et al.
Publicado: (2022)

Systematic Review with Meta-Analysis: Effectiveness and Safety of Acupuncture as Adjuvant Therapy for Side Effects Management in Drug Therapy-Receiving Breast Cancer Patients
por: Chan, Yau-Tuen, et al.
Publicado: (2021)

Pancreatic melatonin enhances anti-tumor immunity in pancreatic adenocarcinoma through regulating tumor-associated neutrophils infiltration and NETosis
por: Chan, Yau-tuen, et al.
Publicado: (2023)

Targeting Hepatic Stellate Cells for the Treatment of Liver Fibrosis by Natural Products: Is It the Dawning of a New Era?
por: Chan, Yau-Tuen, et al.
Publicado: (2020)

Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma
por: Lu, Yuanjun, et al.
Publicado: (2022)

The Role of Protein SUMOylation in Human Hepatocellular Carcinoma: A Potential Target of New Drug Discovery and Development
por: Yuan, Hongchao, et al.
Publicado: (2021)

Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde
por: Wang, Ning, et al.
Publicado: (2017)

PIWIL1 governs the crosstalk of cancer cell metabolism and immunosuppressive microenvironment in hepatocellular carcinoma
por: Wang, Ning, et al.
Publicado: (2021)

Potential Focal Adhesion Kinase Inhibitors in Management of Cancer: Therapeutic Opportunities from Herbal Medicine
por: Chen, Feiyu, et al.
Publicado: (2022)

Genipin-activating PPARγ impedes CCR2-mediated macrophage infiltration into postoperative liver to suppress recurrence of hepatocellular carcinoma
por: Wu, Junyu, et al.
Publicado: (2023)

Lysyl Oxidase‐Like 4 Fosters an Immunosuppressive Microenvironment During Hepatocarcinogenesis
por: Tan, Hor‐Yue, et al.
Publicado: (2021)

Circulating tumor cells in the early detection of human cancers
por: Feng, Zixin, et al.
Publicado: (2022)

Ancient Chinese Medicine Herbal Formula Huanglian Jiedu Decoction as a Neoadjuvant Treatment of Chemotherapy by Improving Diarrhea and Tumor Response
por: Chan, Yau-Tuen, et al.
Publicado: (2020)

The Role of AMP-Activated Protein Kinase as a Potential Target of Treatment of Hepatocellular Carcinoma
por: Jiang, Xue, et al.
Publicado: (2019)

Characterization of cuproptosis in gastric cancer and relationship with clinical and drug reactions
por: Chen, Guoming, et al.
Publicado: (2023)

The toxicology and detoxification of Aconitum: traditional and modern views
por: Chan, Yau-Tuen, et al.
Publicado: (2021)

Cancer Stem Cells: The Potential Targets of Chinese Medicines and Their Active Compounds
por: Hong, Ming, et al.
Publicado: (2016)

GPC2 Is a Potential Diagnostic, Immunological, and Prognostic Biomarker in Pan-Cancer
por: Chen, Guoming, et al.
Publicado: (2022)

Thioredoxin-interacting protein-activated intracellular potassium deprivation mediates the anti-tumour effect of a novel histone acetylation inhibitor HL23, a fangchinoline derivative, in human hepatocellular carcinoma
por: Lu, Yuanjun, et al.
Publicado: (2022)

Atg9b Deficiency Suppresses Autophagy and Potentiates Endoplasmic Reticulum Stress-Associated Hepatocyte Apoptosis in Hepatocarcinogenesis
por: Wang, Ning, et al.
Publicado: (2017)

The functional role of long noncoding RNA in resistance to anticancer treatment
por: Qu, Yidi, et al.
Publicado: (2020)

Targeting Cancer Metabolism to Resensitize Chemotherapy: Potential Development of Cancer Chemosensitizers from Traditional Chinese Medicines
por: Guo, Wei, et al.
Publicado: (2020)

Predictive biomarkers and potential drug combinations of epi-drugs in cancer therapy
por: Yang, Tianshu, et al.
Publicado: (2021)

The Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases
por: Li, Sha, et al.
Publicado: (2018)

Targeting VEGF/VEGFRs Pathway in the Antiangiogenic Treatment of Human Cancers by Traditional Chinese Medicine
por: Zhang, Cheng, et al.
Publicado: (2018)

Hepatoprotective Effects of a Functional Formula of Three Chinese Medicinal Herbs: Experimental Evidence and Network Pharmacology-Based Identification of Mechanism of Action and Potential Bioactive Components
por: Li, Sha, et al.
Publicado: (2018)

MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy
por: Hong, Ming, et al.
Publicado: (2015)

The Significance of Circulating Tumor Cells in Patients with Hepatocellular Carcinoma: Real-Time Monitoring and Moving Targets for Cancer Therapy
por: Chen, Feiyu, et al.
Publicado: (2020)

A Network-Based Pharmacology Study of the Herb-Induced Liver Injury Potential of Traditional Hepatoprotective Chinese Herbal Medicines
por: Hong, Ming, et al.
Publicado: (2017)

Insights into the Role and Interdependence of Oxidative Stress and Inflammation in Liver Diseases
por: Li, Sha, et al.
Publicado: (2016)

Glutamic-Pyruvic Transaminase 1 Facilitates Alternative Fuels for Hepatocellular Carcinoma Growth—A Small Molecule Inhibitor, Berberine
por: Guo, Wei, et al.
Publicado: (2020)

New Natural Pigment Fraction Isolated from Saw Palmetto: Potential for Adjuvant Therapy of Hepatocellular Carcinoma
por: Tan, Hor-Yue, et al.
Publicado: (2016)

The Impacts of Herbal Medicines and Natural Products on Regulating the Hepatic Lipid Metabolism
por: Li, Sha, et al.
Publicado: (2020)

Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future Prospects
por: Hong, Ming, et al.
Publicado: (2015)

Cancer research in an era when epigenetics is no longer “epi”—challenges and opportunities
por: Tao, Qian
Publicado: (2013)

A Novel Epi-drug Therapy Based on the Suppression of BET Family Epigenetic Readers
por: Shin, Dong-Guk, et al.
Publicado: (2017)

Epi‐immunotherapy for cancers: rationales of epi‐drugs in combination with immunotherapy and advances in clinical trials
por: Xu, Yang, et al.
Publicado: (2022)

Uncovering the Anticancer Mechanisms of Chinese Herbal Medicine Formulas: Therapeutic Alternatives for Liver Cancer
por: Chen, Feiyu, et al.
Publicado: (2020)

Recent Insights Into the Role of Immune Cells in Alcoholic Liver Disease
por: Li, Sha, et al.
Publicado: (2019)

The Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human Diseases
por: Tan, Hor-Yue, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_buarnuho1be259oo4fngru8qjs