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MicroRNA-4290 suppresses PDK1-mediated glycolysis to enhance the sensitivity of gastric cancer cell to cisplatin

The development of chemotherapy resistance significantly impairs the efficiency of chemotherapy, but the underlying mechanisms of chemotherapy resistance in gastric cancer (GC) are complicated and still need to be further explored. Here, we aimed to reveal the effects of miR-4290/PDK1 (pyruvate dehy...

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Detalles Bibliográficos
Autores principales:	Qian, Yan, Wu, Xu, Wang, Haixiao, Hou, Guowei, Han, Xiao, Song, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Associação Brasileira de Divulgação Científica 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184963/ https://www.ncbi.nlm.nih.gov/pubmed/32321153 http://dx.doi.org/10.1590/1414-431X20209330

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