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A novel germline gain-of-function HIF2A mutation in hepatocellular carcinoma with polycythemia

Hypoxia-inducible factors (HIFs) regulate oxygen sensing and expression of genes involved in angiogenesis and erythropoiesis. Polycythemia has been observed in patients with hepatocellular carcinoma (HCC), but the underlying molecular basis remains unknown. Liver tissues from 302 HCC patients, inclu...

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Detalles Bibliográficos
Autores principales:	Yu, Jiong, Shi, Xiaowei, Yang, Chunzhang, Bullova, Petra, Hong, Christopher S., Nesvick, Cody L., Dmitriev, Pauline, Pacak, Karel, Zhuang, Zhengping, Cao, Hongcui, Li, Lanjuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185130/ https://www.ncbi.nlm.nih.gov/pubmed/32235007 http://dx.doi.org/10.18632/aging.102967

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