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Genetics of physiological dysregulation: findings from the long life family study using joint models

Recently, Mahalanobis distance (D(M)) was suggested as a statistical measure of physiological dysregulation in aging individuals. We constructed D(M) variants using sets of biomarkers collected at the two visits of the Long Life Family Study (LLFS) and performed joint analyses of longitudinal observ...

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Detalles Bibliográficos
Autores principales: Arbeev, Konstantin G., Bagley, Olivia, Ukraintseva, Svetlana V., Wu, Deqing, Duan, Hongzhe, Kulminski, Alexander M., Stallard, Eric, Christensen, Kaare, Lee, Joseph H., Thyagarajan, Bharat, Zmuda, Joseph M., Yashin, Anatoliy I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185144/
https://www.ncbi.nlm.nih.gov/pubmed/32235003
http://dx.doi.org/10.18632/aging.102987