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Ultrasound, X-ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study
Imaging modalities are not included in The European League Against Rheumatism, The Pediatric Rheumatology International Trials Organization and The Pediatric Rheumatology European Society 2010 criteria for the evaluation of abdominal purpura. The objective of the present study was to compare diagnos...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185176/ https://www.ncbi.nlm.nih.gov/pubmed/32346418 http://dx.doi.org/10.3892/etm.2020.8643 |
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author | Ge, Yurong Liu, Shuchun |
author_facet | Ge, Yurong Liu, Shuchun |
author_sort | Ge, Yurong |
collection | PubMed |
description | Imaging modalities are not included in The European League Against Rheumatism, The Pediatric Rheumatology International Trials Organization and The Pediatric Rheumatology European Society 2010 criteria for the evaluation of abdominal purpura. The objective of the present study was to compare diagnostic parameters of ultrasound, X-ray and computed tomography (CT) for diagnosis of abdominal purpura considering the American College of Rheumatology (ACR) criteria as ‘reference standard’ in children with acute abdominal pain. Medical records of 215 children with acute abdominal pain were reviewed. Data regarding demographics and clinical characteristics, laboratory tests, X-ray, ultrasound findings, and computed tomographic images were collected and analyzed. Decision curve analysis was used for evaluation of the beneficial score for each diagnostic modality. Among diagnostic modalities, CT had the highest sensitivity (0.939); however, ultrasound findings had the highest accuracy (0.861) for diagnosis of abdominal purpura. Unlike X-ray and laboratory tests, ultrasound and CT were successful at detecting abdominal purpura when children had only colicky pain and were aged <20 years; however, occult blood stool test and granulocytes in the walls of small venules and arterioles (biopsy results) were negative. With respect to the ACR criteria, there were seven and three inconclusive results for ultrasound and CT, respectively. Abdominal ultrasound is an easy, non-invasive and safe method for the detection of abdominal purpura in children. |
format | Online Article Text |
id | pubmed-7185176 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-71851762020-04-28 Ultrasound, X-ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study Ge, Yurong Liu, Shuchun Exp Ther Med Articles Imaging modalities are not included in The European League Against Rheumatism, The Pediatric Rheumatology International Trials Organization and The Pediatric Rheumatology European Society 2010 criteria for the evaluation of abdominal purpura. The objective of the present study was to compare diagnostic parameters of ultrasound, X-ray and computed tomography (CT) for diagnosis of abdominal purpura considering the American College of Rheumatology (ACR) criteria as ‘reference standard’ in children with acute abdominal pain. Medical records of 215 children with acute abdominal pain were reviewed. Data regarding demographics and clinical characteristics, laboratory tests, X-ray, ultrasound findings, and computed tomographic images were collected and analyzed. Decision curve analysis was used for evaluation of the beneficial score for each diagnostic modality. Among diagnostic modalities, CT had the highest sensitivity (0.939); however, ultrasound findings had the highest accuracy (0.861) for diagnosis of abdominal purpura. Unlike X-ray and laboratory tests, ultrasound and CT were successful at detecting abdominal purpura when children had only colicky pain and were aged <20 years; however, occult blood stool test and granulocytes in the walls of small venules and arterioles (biopsy results) were negative. With respect to the ACR criteria, there were seven and three inconclusive results for ultrasound and CT, respectively. Abdominal ultrasound is an easy, non-invasive and safe method for the detection of abdominal purpura in children. D.A. Spandidos 2020-06 2020-04-03 /pmc/articles/PMC7185176/ /pubmed/32346418 http://dx.doi.org/10.3892/etm.2020.8643 Text en Copyright: © Ge et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Ge, Yurong Liu, Shuchun Ultrasound, X-ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study |
title | Ultrasound, X-ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study |
title_full | Ultrasound, X-ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study |
title_fullStr | Ultrasound, X-ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study |
title_full_unstemmed | Ultrasound, X-ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study |
title_short | Ultrasound, X-ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: A retrospective study |
title_sort | ultrasound, x-ray, computed tomography and clinical tests for diagnosis of abdominal purpura in children: a retrospective study |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185176/ https://www.ncbi.nlm.nih.gov/pubmed/32346418 http://dx.doi.org/10.3892/etm.2020.8643 |
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