Doxorubicin pretreatment enhances FAPα/survivin co-targeting DNA vaccine anti-tumor activity primarily through decreasing peripheral MDSCs in the 4T1 murine breast cancer model

The tumor microenvironment (TME) provides necessary nutrition for tumor growth and recruits immunosuppressive factors including regulatory T cells and myeloid-derived suppressor cells (MDSCs) to inhibit the anti-tumor immune response induced by immunotherapy. As a main TME component, cancer associat...

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Detalles Bibliográficos
Autores principales: Geng, Fei, Bao, Xin, Dong, Ling, Guo, Qian-Qian, Guo, Jie, Xie, Yu, Zhou, Yi, Yu, Bin, Wu, Hui, Wu, Jia-Xin, Zhang, Hai-Hong, Yu, Xiang-Hui, Kong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185204/
https://www.ncbi.nlm.nih.gov/pubmed/32363118
http://dx.doi.org/10.1080/2162402X.2020.1747350

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