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HIF-1α affects trophoblastic apoptosis involved in the onset of preeclampsia by regulating FOXO3a under hypoxic conditions
Preeclampsia (PE) is a pregnancy-specific syndrome that has severe implications on perinatal mortality and morbidity. Excessive apoptosis of trophoblasts induced by hypoxia may be associated with the development of PE, but the exact pathogenesis is unknown. Forkhead box O transcription factor 3a (FO...
Autores principales: | Zhang, Zhan, Huang, Chenxi, Wang, Ping, Gao, Junjun, Liu, Xin, Li, Yingying, Yan, Shujun, Shi, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185296/ https://www.ncbi.nlm.nih.gov/pubmed/32323858 http://dx.doi.org/10.3892/mmr.2020.11050 |
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