Cargando…

Ketamine promotes the neural differentiation of mouse embryonic stem cells by activating mTOR

Ketamine is a widely used general anesthetic and has been reported to demonstrate neurotoxicity and neuroprotection. Investigation into the regulatory mechanism of ketamine on influencing neural development is of importance for a better and safer way of relieving pain. Reverse transcription-quantita...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Xuhui, Lv, Xiang, Zhang, Lei, Yan, Jia, Hu, Rong, Sun, Yu, Xi, Siwei, Jiang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185302/ https://www.ncbi.nlm.nih.gov/pubmed/32236601 http://dx.doi.org/10.3892/mmr.2020.11043

Ejemplares similares

Mouse embryonic palatal mesenchymal cells maintain stemness through the PTEN-Akt-mTOR autophagic pathway
por: Shi, Lungang, et al.
Publicado: (2019)

PACAP Protects Adult Neural Stem Cells from the Neurotoxic Effect of Ketamine Associated with Decreased Apoptosis, ER Stress and mTOR Pathway Activation
por: Mansouri, Shiva, et al.
Publicado: (2017)

Differential Reponses of Hematopoietic Stem and Progenitor Cells to mTOR Inhibition
por: Yang, Aimin, et al.
Publicado: (2015)

mTOR Signaling and Neural Stem Cells: The Tuberous Sclerosis Complex Model
por: Polchi, Alice, et al.
Publicado: (2018)

FRS2α is Essential for the Fibroblast Growth Factor to Regulate the mTOR Pathway and Autophagy in Mouse Embryonic Fibroblasts
por: Lin, Xiang, et al.
Publicado: (2011)

mTOR Pathway and mTOR Inhibitors in Head and Neck Cancer
por: Gao, Wei, et al.
Publicado: (2012)

Phosphoglycerate dehydrogenase inhibition induces p-mTOR-independent autophagy and promotes multilineage differentiation in embryonal carcinoma stem-like cells
por: Sharif, Tanveer, et al.
Publicado: (2018)

Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells
por: Song, Chengcheng, et al.
Publicado: (2019)

Vascularization in mTOR Mouse Mutants: An Effort Not in Vein
por: Elziny, Soad, et al.
Publicado: (2023)

Ketamine Promotes LPS-Induced Pulmonary Autophagy and Reduces Apoptosis through the AMPK/mTOR Pathway
por: Cao, Jianwei, et al.
Publicado: (2022)

Myelination and mTOR
por: Figlia, Gianluca, et al.
Publicado: (2017)

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
por: Zou, Zhilin, et al.
Publicado: (2020)

Cyclopamine and Rapamycin Synergistically Inhibit mTOR Signalling in Mouse Hepatocytes, Revealing an Interaction of Hedgehog and mTor Signalling in the Liver
por: Spormann, Luise, et al.
Publicado: (2020)

T memory stem cell formation: Caveat mTOR
por: Fowler, Daniel H., et al.
Publicado: (2016)

Akt and mTOR in B Cell Activation and Differentiation
por: Limon, Jose J., et al.
Publicado: (2012)

Regulation of hematopoietic stem cells differentiation, self-renewal, and quiescence through the mTOR signaling pathway
por: Ling, Bai, et al.
Publicado: (2023)

Adiponectin inhibits the differentiation and maturation of osteoclasts via the mTOR pathway in multiple myeloma
por: Liu, Zhaoyun, et al.
Publicado: (2020)

mTOR and ROS regulation by anethole on adipogenic differentiation in human mesenchymal stem cells
por: Rhee, Yun-Hee, et al.
Publicado: (2018)

Dietary protein sources differentially affect microbiota, mTOR activity and transcription of mTOR signaling pathways in the small intestine
por: Kar, Soumya K., et al.
Publicado: (2017)

Protocol for the assessment of mTOR activity in mouse primary hepatocytes
por: Plata-Gómez, Ana Belén, et al.
Publicado: (2021)

AAA + ATPase Thorase inhibits mTOR signaling through the disassembly of the mTOR complex 1
por: Umanah, George K. E., et al.
Publicado: (2022)

mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
por: Tian, Tian, et al.
Publicado: (2019)

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
por: Tiedemann, Kerstin, et al.
Publicado: (2017)

Escaping mTOR inhibition for cancer therapy: Tumor suppressor functions of mTOR
por: Villar, Victor H., et al.
Publicado: (2017)

Overcoming mTOR Resistance Mutations with a New Generation mTOR Inhibitor
por: Rodrik-Outmezguine, Vanessa S., et al.
Publicado: (2016)

Acute administration of ketamine in rats increases hippocampal BDNF and mTOR levels during forced swimming test
por: Yang, Chun, et al.
Publicado: (2013)

P53 and mTOR signalling determine fitness selection through cell competition during early mouse embryonic development
por: Bowling, Sarah, et al.
Publicado: (2018)

Leukemia inhibitory factor (LIF) withdrawal activates mTOR signaling pathway in mouse embryonic stem cells through the MEK/ERK/TSC2 pathway
por: Cherepkova, M Y, et al.
Publicado: (2016)

mTOR and lysosome regulation
por: Puertollano, Rosa
Publicado: (2014)

mTOR, autophagy, and reprogramming
por: Tang, Bor Luen
Publicado: (2014)

Targeting glutaminase and mTOR
por: Tanaka, Kazuhiro, et al.
Publicado: (2015)

mTOR in cerebrovascular disease
por: Van Skike, Candice E., et al.
Publicado: (2019)

mTOR and Tumor Cachexia
por: Duval, Adrian P., et al.
Publicado: (2018)

Double agent mTOR
por: Danzer, Steve C.
Publicado: (2019)

mTOR in Human Diseases
por: Dormond, Olivier
Publicado: (2019)

PI3K/AKT/mTOR Signaling Mediates Valproic Acid-Induced Neuronal Differentiation of Neural Stem Cells through Epigenetic Modifications
por: Zhang, Xi, et al.
Publicado: (2017)

Role of mTOR through Autophagy in Esophageal Cancer Stemness
por: Du, Liang, et al.
Publicado: (2022)

Microvesicles Derived from Human Embryonic Neural Stem Cells Inhibit the Apoptosis of HL-1 Cardiomyocytes by Promoting Autophagy and Regulating AKT and mTOR via Transporting HSP-70
por: Zhang, Lei, et al.
Publicado: (2019)

Interferon regulates neural stem cell function at all ages by orchestrating mTOR and cell cycle
por: Carvajal Ibañez, Damian, et al.
Publicado: (2023)

Commentary: Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor
por: Renna, Maurizio
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_bb06j74o6v63i54f7bhf5c33b4