Antimicrobial and immunomodulatory activity induced by loperamide in mycobacterial infections

• Loperamide modulates macrophages immune responses towards mycobacteria. • Loperamide is an immunoregulator of inflammation during mycobacterial infection. • Loperamide induces immunomodulatory responses and bactericidal mechanisms. • The activation of opioid receptors by loperamide is involved in...

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Detalles Bibliográficos
Autores principales: Juárez, Esmeralda, Ruiz, Andy, Cortez, Omar, Sada, Eduardo, Torres, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185470/
https://www.ncbi.nlm.nih.gov/pubmed/30268801
http://dx.doi.org/10.1016/j.intimp.2018.09.013
Descripción
Sumario:• Loperamide modulates macrophages immune responses towards mycobacteria. • Loperamide is an immunoregulator of inflammation during mycobacterial infection. • Loperamide induces immunomodulatory responses and bactericidal mechanisms. • The activation of opioid receptors by loperamide is involved in its immunomodulatory activity.

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