Interleukin 2 and interleukin 10 function synergistically to promote CD8(+) T cell cytotoxicity, which is suppressed by regulatory T cells in breast cancer

The precise role of interleukin (IL)-10 in breast cancer is not clear. Previous studies suggested a tumor-promoting role of IL-10 in breast cancer, whereas recent discoveries that IL-10 activated and expanded tumor-resident CD8(+) T cells challenged the traditional view. Here, we investigated the ro...

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Detalles Bibliográficos
Autores principales: Li, Xiaogang, Lu, Ping, Li, Bo, Zhang, Wanfu, Yang, Rong, Chu, Yan, Luo, Kaiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185534/
https://www.ncbi.nlm.nih.gov/pubmed/28274688
http://dx.doi.org/10.1016/j.biocel.2017.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185534/
https://www.ncbi.nlm.nih.gov/pubmed/28274688
http://dx.doi.org/10.1016/j.biocel.2017.03.003

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