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Decorin inhibits glucose-induced lens epithelial cell apoptosis via suppressing p22(phox)-p38 MAPK signaling pathway

PURPOSE: To determine the effect of decorin on oxidative stress and apoptosis of human lens epithelial (HLE) cells under high glucose condition. METHODS: HLE cell line (HLEB3) was incubated in normal glucose (5.5 mM) or high glucose (60 mM) medium. Decorin (50 nM) was applied 2 hours before high glu...

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Detalles Bibliográficos
Autores principales:	Du, Shanshan, Shao, Jingzhi, Xie, Dandan, Zhang, Fengyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185589/ https://www.ncbi.nlm.nih.gov/pubmed/32339204 http://dx.doi.org/10.1371/journal.pone.0224251

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